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Neuroprotective effects of an engineered Escherichia coli Nissle 1917 on Parkinson's disease in mice by delivering GLP‐1 and modulating gut microbiota

Considerable evidence suggests that insulin resistance is closely linked to Parkinson's disease (PD), leading to agents aiming at treating diabetes can be regarded as new neuroprotective strategies in PD, notably glucagon‐like peptide‐1 (GLP‐1). However, the extremely short half‐life of GLP‐1 d...

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Detalles Bibliográficos
Autores principales: Wu, Heng, Wei, Jing, Zhao, Xiumiao, Liu, Ying, Chen, Zhihang, Wei, Kehong, Lu, Jiachen, Chen, Wenjie, Jiang, Meixiu, Li, Shengjie, Chen, Tingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487327/
https://www.ncbi.nlm.nih.gov/pubmed/37693045
http://dx.doi.org/10.1002/btm2.10351