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Use of hepatic support with MARS in a patient with SARS-CoV-2 Pneumonia, in treatment with ECMO and CRRT therapies: Case Report

Extracorporeal Membrane Oxygenation (ECMO) therapy had an important role in the treatment of severe COVID-19 pneumonia, where invasive mechanical ventilation was not enough to provide correct oxygenation to various organ systems. However, there are other extracorporeal technologies, such as the Mole...

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Autores principales: Villarreal-Ondarza, Irma, Rodríguez-Salinas, Cesar Alejandro, Gómez-Gutierrez, Rene, Guerrero-Izaguirre, Israel, Rizo-Topete, Lilia María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487337/
https://www.ncbi.nlm.nih.gov/pubmed/37682211
http://dx.doi.org/10.1051/ject/2023025
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author Villarreal-Ondarza, Irma
Rodríguez-Salinas, Cesar Alejandro
Gómez-Gutierrez, Rene
Guerrero-Izaguirre, Israel
Rizo-Topete, Lilia María
author_facet Villarreal-Ondarza, Irma
Rodríguez-Salinas, Cesar Alejandro
Gómez-Gutierrez, Rene
Guerrero-Izaguirre, Israel
Rizo-Topete, Lilia María
author_sort Villarreal-Ondarza, Irma
collection PubMed
description Extracorporeal Membrane Oxygenation (ECMO) therapy had an important role in the treatment of severe COVID-19 pneumonia, where invasive mechanical ventilation was not enough to provide correct oxygenation to various organ systems. However, there are other extracorporeal technologies, such as the Molecular Absorbent Recirculation System (MARS) and Continuous Renal Replacement Therapy (CRRT), that provide temporal support for any critical patient. The following case describes a 60-year-old man with severe Acute Respiratory Distress Syndrome (ARDS), who needed ECMO therapy. During the critical days of hospitalization, CRRT was used, but a sudden hyperbilirubinemia ensued. Consequently, MARS therapy was initiated; followed by an improvement of bilirubin levels. Additional studies are needed to establish the possible benefits of the combination of MARS therapy and ECMO; however, we detected that concomitantly, there was a decrease in other laboratory parameters such as acute phase reactants. Even though, no change in clinical course was observed, as shown in some studies.
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spelling pubmed-104873372023-09-09 Use of hepatic support with MARS in a patient with SARS-CoV-2 Pneumonia, in treatment with ECMO and CRRT therapies: Case Report Villarreal-Ondarza, Irma Rodríguez-Salinas, Cesar Alejandro Gómez-Gutierrez, Rene Guerrero-Izaguirre, Israel Rizo-Topete, Lilia María J Extra Corpor Technol Case Report Extracorporeal Membrane Oxygenation (ECMO) therapy had an important role in the treatment of severe COVID-19 pneumonia, where invasive mechanical ventilation was not enough to provide correct oxygenation to various organ systems. However, there are other extracorporeal technologies, such as the Molecular Absorbent Recirculation System (MARS) and Continuous Renal Replacement Therapy (CRRT), that provide temporal support for any critical patient. The following case describes a 60-year-old man with severe Acute Respiratory Distress Syndrome (ARDS), who needed ECMO therapy. During the critical days of hospitalization, CRRT was used, but a sudden hyperbilirubinemia ensued. Consequently, MARS therapy was initiated; followed by an improvement of bilirubin levels. Additional studies are needed to establish the possible benefits of the combination of MARS therapy and ECMO; however, we detected that concomitantly, there was a decrease in other laboratory parameters such as acute phase reactants. Even though, no change in clinical course was observed, as shown in some studies. EDP Sciences 2023-09-08 /pmc/articles/PMC10487337/ /pubmed/37682211 http://dx.doi.org/10.1051/ject/2023025 Text en © The Author(s), published by EDP Sciences, 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Villarreal-Ondarza, Irma
Rodríguez-Salinas, Cesar Alejandro
Gómez-Gutierrez, Rene
Guerrero-Izaguirre, Israel
Rizo-Topete, Lilia María
Use of hepatic support with MARS in a patient with SARS-CoV-2 Pneumonia, in treatment with ECMO and CRRT therapies: Case Report
title Use of hepatic support with MARS in a patient with SARS-CoV-2 Pneumonia, in treatment with ECMO and CRRT therapies: Case Report
title_full Use of hepatic support with MARS in a patient with SARS-CoV-2 Pneumonia, in treatment with ECMO and CRRT therapies: Case Report
title_fullStr Use of hepatic support with MARS in a patient with SARS-CoV-2 Pneumonia, in treatment with ECMO and CRRT therapies: Case Report
title_full_unstemmed Use of hepatic support with MARS in a patient with SARS-CoV-2 Pneumonia, in treatment with ECMO and CRRT therapies: Case Report
title_short Use of hepatic support with MARS in a patient with SARS-CoV-2 Pneumonia, in treatment with ECMO and CRRT therapies: Case Report
title_sort use of hepatic support with mars in a patient with sars-cov-2 pneumonia, in treatment with ecmo and crrt therapies: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487337/
https://www.ncbi.nlm.nih.gov/pubmed/37682211
http://dx.doi.org/10.1051/ject/2023025
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