PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves

BACKGROUND: Cardiac valve disease is observed in 2.5% of the general population and 10% of the elderly people. Effective pharmacological treatments are currently not available, and patients with severe cardiac valve disease require surgery. PROX1 (prospero-related homeobox transcription factor 1) an...

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Detalles Bibliográficos
Autores principales: Ho, Yen-Chun, Geng, Xin, O’Donnell, Anna, Ibarrola, Jaime, Fernandez-Celis, Amaya, Varshney, Rohan, Subramani, Kumar, Azartash-Namin, Zheila J., Kim, Jang, Silasi, Robert, Wylie-Sears, Jill, Alvandi, Zahra, Chen, Lijuan, Cha, Boksik, Chen, Hong, Xia, Lijun, Zhou, Bin, Lupu, Florea, Burkhart, Harold M., Aikawa, Elena, Olson, Lorin E., Ahamed, Jasimuddin, López-Andrés, Natalia, Bischoff, Joyce, Yutzey, Katherine E., Srinivasan, R. Sathish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487359/
https://www.ncbi.nlm.nih.gov/pubmed/37555328
http://dx.doi.org/10.1161/CIRCRESAHA.123.323027

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