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Dual Modulator of ASIC Channels and GABA(A) Receptors from Thyme Alters Fear-Related Hippocampal Activity

Acid-sensing ion channels (ASICs) are proton-gated ion channels that mediate nociception in the peripheral nervous system and contribute to fear and learning in the central nervous system. Sevanol was reported previously as a naturally-occurring ASIC inhibitor from thyme with favorable analgesic and...

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Detalles Bibliográficos
Autores principales: Kalinovskii, Aleksandr P., Pushkarev, Anton P., Mikhailenko, Anastasia D., Kudryavtsev, Denis S., Belozerova, Olga A., Shmygarev, Vladimir I., Yatskin, Oleg N., Korolkova, Yuliya V., Kozlov, Sergey A., Osmakov, Dmitry I., Popov, Alexander, Andreev, Yaroslav A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487430/
https://www.ncbi.nlm.nih.gov/pubmed/37685955
http://dx.doi.org/10.3390/ijms241713148