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Dual Modulator of ASIC Channels and GABA(A) Receptors from Thyme Alters Fear-Related Hippocampal Activity
Acid-sensing ion channels (ASICs) are proton-gated ion channels that mediate nociception in the peripheral nervous system and contribute to fear and learning in the central nervous system. Sevanol was reported previously as a naturally-occurring ASIC inhibitor from thyme with favorable analgesic and...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487430/ https://www.ncbi.nlm.nih.gov/pubmed/37685955 http://dx.doi.org/10.3390/ijms241713148 |