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Dual Modulator of ASIC Channels and GABA(A) Receptors from Thyme Alters Fear-Related Hippocampal Activity
Acid-sensing ion channels (ASICs) are proton-gated ion channels that mediate nociception in the peripheral nervous system and contribute to fear and learning in the central nervous system. Sevanol was reported previously as a naturally-occurring ASIC inhibitor from thyme with favorable analgesic and...
Autores principales: | Kalinovskii, Aleksandr P., Pushkarev, Anton P., Mikhailenko, Anastasia D., Kudryavtsev, Denis S., Belozerova, Olga A., Shmygarev, Vladimir I., Yatskin, Oleg N., Korolkova, Yuliya V., Kozlov, Sergey A., Osmakov, Dmitry I., Popov, Alexander, Andreev, Yaroslav A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487430/ https://www.ncbi.nlm.nih.gov/pubmed/37685955 http://dx.doi.org/10.3390/ijms241713148 |
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