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17 β-Estradiol Impedes Aortic Root Dilation and Rupture in Male Marfan Mice

Marfan syndrome causes a hereditary form of thoracic aortic aneurysms with worse outcomes in male compared to female patients. In this study, we examine the effects of 17 β-estradiol on aortic dilation and rupture in a Marfan mouse model. Marfan male mice were administered 17 β-estradiol, and the gr...

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Detalles Bibliográficos
Autores principales: Saddic, Louis, Escopete, Sean, Zilberberg, Lior, Kalsow, Shannon, Gupta, Divya, Eghbali, Mansoureh, Parker, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487461/
https://www.ncbi.nlm.nih.gov/pubmed/37686377
http://dx.doi.org/10.3390/ijms241713571

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