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Regulation of Glycoprotein VI-Dependent Platelet Activation and Thrombus Formation by Heparan Sulfate Proteoglycan Perlecan

Proteoglycans form a heterogeneous family of proteins with covalently bound sulfated glycosaminoglycans. The extracellular matrix proteoglycan perlecan has been proposed to bind to the platelet- and megakaryocyte-specific receptor G6bB, co-regulating platelet glycoprotein VI (GPVI) signaling. The de...

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Detalles Bibliográficos
Autores principales:	Provenzale, Isabella, De Simone, Ilaria, Gibbins, Jonathan M., Heemskerk, Johan W. M., van der Meijden, Paola E. J., Jones, Chris I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487520/ https://www.ncbi.nlm.nih.gov/pubmed/37686158 http://dx.doi.org/10.3390/ijms241713352

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