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Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group

Asthma is the most frequent chronic disease of childhood, affecting up to 20% of children worldwide. The main guidelines on asthma maintenance therapy in pediatrics suggest different approaches and describe different stages of asthma to determine the most appropriate treatment. This project aims to...

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Autores principales: Fainardi, Valentina, Caffarelli, Carlo, Deolmi, Michela, Zambelli, Giulia, Palazzolo, Elisabetta, Scavone, Sara, Bergamini, Barbara Maria, Bertelli, Luca, Biserna, Loretta, Bottau, Paolo, Corinaldesi, Elena, De Paulis, Nicoletta, Di Palmo, Emanuela, Dondi, Arianna, Gallucci, Marcella, Guidi, Battista, Lombardi, Francesca, Magistrali, Maria Sole, Marastoni, Elisabetta, Pastorelli, Silvia, Piccorossi, Alessandra, Poloni, Maurizio, Tagliati, Sylvie, Vaienti, Francesca, Gregori, Giuseppe, Sacchetti, Roberto, Antodaro, Francesco, Bergomi, Andrea, Reggiani, Lamberto, De Fanti, Alessandro, Marchetti, Federico, Grandinetti, Roberto, Mussi, Nicole, Ricci, Giampaolo, Esposito, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487522/
https://www.ncbi.nlm.nih.gov/pubmed/37685533
http://dx.doi.org/10.3390/jcm12175467
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author Fainardi, Valentina
Caffarelli, Carlo
Deolmi, Michela
Zambelli, Giulia
Palazzolo, Elisabetta
Scavone, Sara
Bergamini, Barbara Maria
Bertelli, Luca
Biserna, Loretta
Bottau, Paolo
Corinaldesi, Elena
De Paulis, Nicoletta
Di Palmo, Emanuela
Dondi, Arianna
Gallucci, Marcella
Guidi, Battista
Lombardi, Francesca
Magistrali, Maria Sole
Marastoni, Elisabetta
Pastorelli, Silvia
Piccorossi, Alessandra
Poloni, Maurizio
Tagliati, Sylvie
Vaienti, Francesca
Gregori, Giuseppe
Sacchetti, Roberto
Antodaro, Francesco
Bergomi, Andrea
Reggiani, Lamberto
De Fanti, Alessandro
Marchetti, Federico
Grandinetti, Roberto
Mussi, Nicole
Ricci, Giampaolo
Esposito, Susanna
author_facet Fainardi, Valentina
Caffarelli, Carlo
Deolmi, Michela
Zambelli, Giulia
Palazzolo, Elisabetta
Scavone, Sara
Bergamini, Barbara Maria
Bertelli, Luca
Biserna, Loretta
Bottau, Paolo
Corinaldesi, Elena
De Paulis, Nicoletta
Di Palmo, Emanuela
Dondi, Arianna
Gallucci, Marcella
Guidi, Battista
Lombardi, Francesca
Magistrali, Maria Sole
Marastoni, Elisabetta
Pastorelli, Silvia
Piccorossi, Alessandra
Poloni, Maurizio
Tagliati, Sylvie
Vaienti, Francesca
Gregori, Giuseppe
Sacchetti, Roberto
Antodaro, Francesco
Bergomi, Andrea
Reggiani, Lamberto
De Fanti, Alessandro
Marchetti, Federico
Grandinetti, Roberto
Mussi, Nicole
Ricci, Giampaolo
Esposito, Susanna
author_sort Fainardi, Valentina
collection PubMed
description Asthma is the most frequent chronic disease of childhood, affecting up to 20% of children worldwide. The main guidelines on asthma maintenance therapy in pediatrics suggest different approaches and describe different stages of asthma to determine the most appropriate treatment. This project aims to summarize the most recent evidence regarding maintenance therapy for asthma in children and adolescents. A multidisciplinary panel of experts was asked clinical questions regarding the treatment of children and adolescents with asthma. Overall, 10 clinical questions were addressed, and the search strategy included accessing electronic databases and a manual search of gray literature published in the last 25 years. After data extraction and narrative synthesis of results, recommendations were developed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) methodology. Results showed that the choice of medication depends on the severity of the child’s asthma, phenotype, age, preference, and individual factors. In addition to medications, the identification of comorbidities and modifiable factors is crucial to obtaining good control. Asthma in children is heterogeneous, and its evolution varies over time. Since most recommendations for asthma management in childhood are extrapolated from clinical studies performed in adults, more clinical trials specifically designed for young children should be conducted.
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spelling pubmed-104875222023-09-09 Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group Fainardi, Valentina Caffarelli, Carlo Deolmi, Michela Zambelli, Giulia Palazzolo, Elisabetta Scavone, Sara Bergamini, Barbara Maria Bertelli, Luca Biserna, Loretta Bottau, Paolo Corinaldesi, Elena De Paulis, Nicoletta Di Palmo, Emanuela Dondi, Arianna Gallucci, Marcella Guidi, Battista Lombardi, Francesca Magistrali, Maria Sole Marastoni, Elisabetta Pastorelli, Silvia Piccorossi, Alessandra Poloni, Maurizio Tagliati, Sylvie Vaienti, Francesca Gregori, Giuseppe Sacchetti, Roberto Antodaro, Francesco Bergomi, Andrea Reggiani, Lamberto De Fanti, Alessandro Marchetti, Federico Grandinetti, Roberto Mussi, Nicole Ricci, Giampaolo Esposito, Susanna J Clin Med Article Asthma is the most frequent chronic disease of childhood, affecting up to 20% of children worldwide. The main guidelines on asthma maintenance therapy in pediatrics suggest different approaches and describe different stages of asthma to determine the most appropriate treatment. This project aims to summarize the most recent evidence regarding maintenance therapy for asthma in children and adolescents. A multidisciplinary panel of experts was asked clinical questions regarding the treatment of children and adolescents with asthma. Overall, 10 clinical questions were addressed, and the search strategy included accessing electronic databases and a manual search of gray literature published in the last 25 years. After data extraction and narrative synthesis of results, recommendations were developed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) methodology. Results showed that the choice of medication depends on the severity of the child’s asthma, phenotype, age, preference, and individual factors. In addition to medications, the identification of comorbidities and modifiable factors is crucial to obtaining good control. Asthma in children is heterogeneous, and its evolution varies over time. Since most recommendations for asthma management in childhood are extrapolated from clinical studies performed in adults, more clinical trials specifically designed for young children should be conducted. MDPI 2023-08-23 /pmc/articles/PMC10487522/ /pubmed/37685533 http://dx.doi.org/10.3390/jcm12175467 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fainardi, Valentina
Caffarelli, Carlo
Deolmi, Michela
Zambelli, Giulia
Palazzolo, Elisabetta
Scavone, Sara
Bergamini, Barbara Maria
Bertelli, Luca
Biserna, Loretta
Bottau, Paolo
Corinaldesi, Elena
De Paulis, Nicoletta
Di Palmo, Emanuela
Dondi, Arianna
Gallucci, Marcella
Guidi, Battista
Lombardi, Francesca
Magistrali, Maria Sole
Marastoni, Elisabetta
Pastorelli, Silvia
Piccorossi, Alessandra
Poloni, Maurizio
Tagliati, Sylvie
Vaienti, Francesca
Gregori, Giuseppe
Sacchetti, Roberto
Antodaro, Francesco
Bergomi, Andrea
Reggiani, Lamberto
De Fanti, Alessandro
Marchetti, Federico
Grandinetti, Roberto
Mussi, Nicole
Ricci, Giampaolo
Esposito, Susanna
Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group
title Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group
title_full Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group
title_fullStr Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group
title_full_unstemmed Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group
title_short Maintenance Therapy for Children and Adolescents with Asthma: Guidelines and Recommendations from the Emilia-Romagna Asthma (ERA) Study Group
title_sort maintenance therapy for children and adolescents with asthma: guidelines and recommendations from the emilia-romagna asthma (era) study group
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487522/
https://www.ncbi.nlm.nih.gov/pubmed/37685533
http://dx.doi.org/10.3390/jcm12175467
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