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Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH)

Background: Increasing numbers of long-term gastrointestinal (GI) cancer survivors highlight the importance of understanding the factors contributing to their health-related quality of life (HRQoL). We investigated the risk factors of HRQoL, including demographics, clinical characteristics, and soci...

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Autores principales: Han, Claire J., Tounkara, Fode, Kalady, Matthew, Noonan, Anne M., Burse, Natasha R., Paskett, Electra D., Von Ah, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487530/
https://www.ncbi.nlm.nih.gov/pubmed/37681816
http://dx.doi.org/10.3390/ijerph20176676
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author Han, Claire J.
Tounkara, Fode
Kalady, Matthew
Noonan, Anne M.
Burse, Natasha R.
Paskett, Electra D.
Von Ah, Diane
author_facet Han, Claire J.
Tounkara, Fode
Kalady, Matthew
Noonan, Anne M.
Burse, Natasha R.
Paskett, Electra D.
Von Ah, Diane
author_sort Han, Claire J.
collection PubMed
description Background: Increasing numbers of long-term gastrointestinal (GI) cancer survivors highlight the importance of understanding the factors contributing to their health-related quality of life (HRQoL). We investigated the risk factors of HRQoL, including demographics, clinical characteristics, and social and behavioral determinants of health (SBDH). Methods: Data on adult GI cancer survivors (n = 3201) from the Behavioral Risk Factors Surveillance System (BRFSS) surveys from 2014–2021 (except for 2015) were analyzed. Unadjusted/adjusted logistic regression was used. Results: The majority were women (54%) and white (78%), with a median age of 67. Survivors who were 65 years or older, diagnosed with colorectal cancer, or who had fewer comorbidities were more likely to report significantly better HRQoL. Significant social factors of poor HRQoL included unmarried, racial and ethnic minorities, poor socioeconomic status, and poor healthcare access. Significant behavioral factors of poor HRQoL were lack of physical activity, heavy alcohol consumption, and current smoking, with lack of physical activity being the most significant factor. Conclusions: The SBDH has a critical role in HRQoL. Future studies are warranted to develop a tailored survivorship intervention, such as physical rehabilitation, and to explore machine learning/artificial intelligence-based predictive models to identify cancer survivors at a high risk of developing poor HRQoL.
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spelling pubmed-104875302023-09-09 Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH) Han, Claire J. Tounkara, Fode Kalady, Matthew Noonan, Anne M. Burse, Natasha R. Paskett, Electra D. Von Ah, Diane Int J Environ Res Public Health Article Background: Increasing numbers of long-term gastrointestinal (GI) cancer survivors highlight the importance of understanding the factors contributing to their health-related quality of life (HRQoL). We investigated the risk factors of HRQoL, including demographics, clinical characteristics, and social and behavioral determinants of health (SBDH). Methods: Data on adult GI cancer survivors (n = 3201) from the Behavioral Risk Factors Surveillance System (BRFSS) surveys from 2014–2021 (except for 2015) were analyzed. Unadjusted/adjusted logistic regression was used. Results: The majority were women (54%) and white (78%), with a median age of 67. Survivors who were 65 years or older, diagnosed with colorectal cancer, or who had fewer comorbidities were more likely to report significantly better HRQoL. Significant social factors of poor HRQoL included unmarried, racial and ethnic minorities, poor socioeconomic status, and poor healthcare access. Significant behavioral factors of poor HRQoL were lack of physical activity, heavy alcohol consumption, and current smoking, with lack of physical activity being the most significant factor. Conclusions: The SBDH has a critical role in HRQoL. Future studies are warranted to develop a tailored survivorship intervention, such as physical rehabilitation, and to explore machine learning/artificial intelligence-based predictive models to identify cancer survivors at a high risk of developing poor HRQoL. MDPI 2023-08-29 /pmc/articles/PMC10487530/ /pubmed/37681816 http://dx.doi.org/10.3390/ijerph20176676 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Han, Claire J.
Tounkara, Fode
Kalady, Matthew
Noonan, Anne M.
Burse, Natasha R.
Paskett, Electra D.
Von Ah, Diane
Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH)
title Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH)
title_full Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH)
title_fullStr Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH)
title_full_unstemmed Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH)
title_short Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH)
title_sort risk factors of health-related quality of life among gastrointestinal cancer survivors in the u.s.: with a focus on social and behavioral determinants of health (sbdh)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487530/
https://www.ncbi.nlm.nih.gov/pubmed/37681816
http://dx.doi.org/10.3390/ijerph20176676
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