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Comparison Study between Artificial Urinary Sphincter and Adjustable Male Sling: A Propensity-Score-Matched Analysis

Aims: This study aimed to compare the outcomes of the AUS and an adjustable male sling (ATOMS(TM)). Methods: It was a retrospective observational cohort study with two arms. Propensity score matching (PSM) was performed in order to limit selection bias and, consequently, a comparison between groups...

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Autores principales: Geretto, Paolo, Ammirati, Enrico, Falcone, Marco, Manassero, Alberto, Agnello, Marco, Della Corte, Marcello, Gontero, Paolo, Giammò, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487594/
https://www.ncbi.nlm.nih.gov/pubmed/37685552
http://dx.doi.org/10.3390/jcm12175489
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author Geretto, Paolo
Ammirati, Enrico
Falcone, Marco
Manassero, Alberto
Agnello, Marco
Della Corte, Marcello
Gontero, Paolo
Giammò, Alessandro
author_facet Geretto, Paolo
Ammirati, Enrico
Falcone, Marco
Manassero, Alberto
Agnello, Marco
Della Corte, Marcello
Gontero, Paolo
Giammò, Alessandro
author_sort Geretto, Paolo
collection PubMed
description Aims: This study aimed to compare the outcomes of the AUS and an adjustable male sling (ATOMS(TM)). Methods: It was a retrospective observational cohort study with two arms. Propensity score matching (PSM) was performed in order to limit selection bias and, consequently, a comparison between groups in terms of functional outcomes (24 h pad test and perception of improvement questionnaires), complications (overall complications, high-grade complications, reinterventions and explantations) and device survival was performed. Results: 49 patients in both arms were included. The baseline characteristics were similar between the groups. The mean follow up was 43 ± 35 months. Dryness was achieved in 22 patients (44.9%) in the AUS group and 11 (22.5%) in the sling group (p = 0.03). A total of 40 patients declared themselves well improved in the sling group (81%), while 35 (71%) declared the same in the AUS group (p = 0.78). The AUS was associated with more high-grade complications, reinterventions and explantations than the ATOMS(TM). Survival at 60 months was 82 ± 9% in the sling group and 67 ± 7% in the AUS group (p = 0.03). Conclusions: While the AUS may be characterized by a higher dry rate, it has an increased risk of high-grade complications and reinterventions. It is proposed that the ATOMS prosthesis can be successfully used for patients who require a less invasive procedure that maintains good functional outcomes.
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spelling pubmed-104875942023-09-09 Comparison Study between Artificial Urinary Sphincter and Adjustable Male Sling: A Propensity-Score-Matched Analysis Geretto, Paolo Ammirati, Enrico Falcone, Marco Manassero, Alberto Agnello, Marco Della Corte, Marcello Gontero, Paolo Giammò, Alessandro J Clin Med Article Aims: This study aimed to compare the outcomes of the AUS and an adjustable male sling (ATOMS(TM)). Methods: It was a retrospective observational cohort study with two arms. Propensity score matching (PSM) was performed in order to limit selection bias and, consequently, a comparison between groups in terms of functional outcomes (24 h pad test and perception of improvement questionnaires), complications (overall complications, high-grade complications, reinterventions and explantations) and device survival was performed. Results: 49 patients in both arms were included. The baseline characteristics were similar between the groups. The mean follow up was 43 ± 35 months. Dryness was achieved in 22 patients (44.9%) in the AUS group and 11 (22.5%) in the sling group (p = 0.03). A total of 40 patients declared themselves well improved in the sling group (81%), while 35 (71%) declared the same in the AUS group (p = 0.78). The AUS was associated with more high-grade complications, reinterventions and explantations than the ATOMS(TM). Survival at 60 months was 82 ± 9% in the sling group and 67 ± 7% in the AUS group (p = 0.03). Conclusions: While the AUS may be characterized by a higher dry rate, it has an increased risk of high-grade complications and reinterventions. It is proposed that the ATOMS prosthesis can be successfully used for patients who require a less invasive procedure that maintains good functional outcomes. MDPI 2023-08-24 /pmc/articles/PMC10487594/ /pubmed/37685552 http://dx.doi.org/10.3390/jcm12175489 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Geretto, Paolo
Ammirati, Enrico
Falcone, Marco
Manassero, Alberto
Agnello, Marco
Della Corte, Marcello
Gontero, Paolo
Giammò, Alessandro
Comparison Study between Artificial Urinary Sphincter and Adjustable Male Sling: A Propensity-Score-Matched Analysis
title Comparison Study between Artificial Urinary Sphincter and Adjustable Male Sling: A Propensity-Score-Matched Analysis
title_full Comparison Study between Artificial Urinary Sphincter and Adjustable Male Sling: A Propensity-Score-Matched Analysis
title_fullStr Comparison Study between Artificial Urinary Sphincter and Adjustable Male Sling: A Propensity-Score-Matched Analysis
title_full_unstemmed Comparison Study between Artificial Urinary Sphincter and Adjustable Male Sling: A Propensity-Score-Matched Analysis
title_short Comparison Study between Artificial Urinary Sphincter and Adjustable Male Sling: A Propensity-Score-Matched Analysis
title_sort comparison study between artificial urinary sphincter and adjustable male sling: a propensity-score-matched analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487594/
https://www.ncbi.nlm.nih.gov/pubmed/37685552
http://dx.doi.org/10.3390/jcm12175489
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