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Influence of Bruton’s Tyrosine Kinase (BTK) on Epithelial–Mesenchymal Transition (EMT) Processes and Cancer Stem Cell (CSC) Enrichment in Head and Neck Squamous Cell Carcinoma (HNSCC)
Constitutively active kinases play a crucial role in carcinogenesis, and their inhibition is a common target for molecular tumor therapy. We recently discovered the expression of two oncogenic isoforms of Bruton’s Tyrosine Kinase (BTK) in head and neck squamous cell carcinoma (HNSCC), Btk-p80 and BT...
Autores principales: | Leichtle, Franziska, Betzler, Annika C., Eizenberger, Carlotta, Lesakova, Kristina, Ezić, Jasmin, Drees, Robert, Greve, Jens, Schuler, Patrick J., Laban, Simon, Hoffmann, Thomas K., Cordes, Nils, Lavitrano, Marialuisa, Grassilli, Emanuela, Brunner, Cornelia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487612/ https://www.ncbi.nlm.nih.gov/pubmed/37685940 http://dx.doi.org/10.3390/ijms241713133 |
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