Cargando…

miRNAs Epigenetic Tuning of Wall Remodeling in the Early Phase after Myocardial Infarction: A Novel Epidrug Approach

Myocardial infarction (MI) is one of the leading causes of death in Western countries. An early diagnosis decreases subsequent severe complications such as wall remodeling or heart failure and improves treatments and interventions. Novel therapeutic targets have been recognized and, together with th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salvatori, Francesca, D’Aversa, Elisabetta, Serino, Maria Luisa, Singh, Ajay Vikram, Secchiero, Paola, Zauli, Giorgio, Tisato, Veronica, Gemmati, Donato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487654/ https://www.ncbi.nlm.nih.gov/pubmed/37686073 http://dx.doi.org/10.3390/ijms241713268

Ejemplares similares

Maternal Haplotypes in DHFR Promoter and MTHFR Gene in Tuning Childhood Acute Lymphoblastic Leukemia Onset-Latency: Genetic/Epigenetic Mother/Child Dyad Study (GEMCDS)
por: Tisato, Veronica, et al.
Publicado: (2019)

COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-Chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males?
por: Gemmati, Donato, et al.
Publicado: (2020)

p53/NF-kB Balance in SARS-CoV-2 Infection: From OMICs, Genomics and Pharmacogenomics Insights to Tailored Therapeutic Perspectives (COVIDomics)
por: Milani, Daniela, et al.
Publicado: (2022)

Host genetics impact on SARS-CoV-2 vaccine-induced immunoglobulin levels and dynamics: The role of TP53, ABO, APOE, ACE2, HLA-A, and CRP genes
por: Gemmati, Donato, et al.
Publicado: (2022)

Sex/Gender-Specific Imbalance in CVD: Could Physical Activity Help to Improve Clinical Outcome Targeting CVD Molecular Mechanisms in Women?
por: Vaccarezza, Mauro, et al.
Publicado: (2020)

TRAIL, OPG, and TWEAK in kidney disease: biomarkers or therapeutic targets?
por: Bernardi, Stella, et al.
Publicado: (2019)

Epigenetic Regulation in Breast Cancer: Insights on Epidrugs
por: Kim, Ayoung, et al.
Publicado: (2023)

Rationale for Considering Oral Idasanutlin as a Therapeutic Option for COVID-19 Patients
por: Zauli, Giorgio, et al.
Publicado: (2020)

Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in cognitive impairment diseases
por: Tisato, Veronica, et al.
Publicado: (2018)

Lipids at the Nexus between Cerebrovascular Disease and Vascular Dementia: The Impact of HDL-Cholesterol and Ceramides
por: Sergi, Domenico, et al.
Publicado: (2023)

Natural and Synthetic Anticancer Epidrugs Targeting the Epigenetic Integrator UHRF1
por: Ashraf, Waseem, et al.
Publicado: (2023)

Clinical perspectives of TRAIL: insights into central nervous system disorders
por: Tisato, Veronica, et al.
Publicado: (2016)

MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer
por: Tisato, Veronica, et al.
Publicado: (2017)

Genetic Hypothesis and Pharmacogenetics Side of Renin-Angiotensin-System in COVID-19
por: Gemmati, Donato, et al.
Publicado: (2020)

Genetics and Epigenetics of One-Carbon Metabolism Pathway in Autism Spectrum Disorder: A Sex-Specific Brain Epigenome?
por: Tisato, Veronica, et al.
Publicado: (2021)

Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy
por: Tisato, Veronica, et al.
Publicado: (2015)

Epidrugs: novel epigenetic regulators that open a new window for targeting osteoblast differentiation
por: Ghorbaninejad, Mahsa, et al.
Publicado: (2020)

Targeting Epigenetic Regulatory Enzymes for Cancer Therapeutics: Novel Small-Molecule Epidrug Development
por: Jin, Ye, et al.
Publicado: (2022)

Serum TRAIL levels increase shortly after insulin therapy and metabolic stabilization in children with type 1 diabetes mellitus
por: Tornese, Gianluca, et al.
Publicado: (2015)

Epidrugs: Toward Understanding and Treating Diverse Diseases
por: Umehara, Takashi
Publicado: (2022)

Screening Readthrough Compounds to Suppress Nonsense Mutations: Possible Application to β-Thalassemia
por: Borgatti, Monica, et al.
Publicado: (2020)

Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women
por: Tisato, Veronica, et al.
Publicado: (2017)

TRAIL/DR5 pathway promotes AKT phosphorylation, skeletal muscle differentiation, and glucose uptake
por: Toffoli, Barbara, et al.
Publicado: (2021)

The γ-secretase inhibitors enhance the anti-leukemic activity of ibrutinib in B-CLL cells
por: Secchiero, Paola, et al.
Publicado: (2017)

The Role of Epigenetic Modifications in Human Cancers and the Use of Natural Compounds as Epidrugs: Mechanistic Pathways and Pharmacodynamic Actions
por: Bouyahya, Abdelhakim, et al.
Publicado: (2022)

Phytochemicals as Potential Epidrugs in Type 2 Diabetes Mellitus
por: Ramírez-Alarcón, Karina, et al.
Publicado: (2021)

Modulation of Circulating Cytokine-Chemokine Profile in Patients Affected by Chronic Venous Insufficiency Undergoing Surgical Hemodynamic Correction
por: Tisato, Veronica, et al.
Publicado: (2014)

GM-CSF Exhibits Anti-Inflammatory Activity on Endothelial Cells Derived from Chronic Venous Disease Patients
por: Tisato, Veronica, et al.
Publicado: (2013)

Inhibitory Effect of Natural Anti-Inflammatory Compounds on Cytokines Released by Chronic Venous Disease Patient-Derived Endothelial Cells
por: Tisato, Veronica, et al.
Publicado: (2013)

In Vitro Endothelial Cell Proliferation Assay Reveals Distinct Levels of Proangiogenic Cytokines Characterizing Sera of Healthy Subjects and of Patients with Heart Failure
por: Voltan, Rebecca, et al.
Publicado: (2014)

Inherited genetic predispositions in F13A1 and F13B genes predict abdominal adhesion formation: identification of gender prognostic indicators
por: Gemmati, Donato, et al.
Publicado: (2018)

Overcoming of Microenvironment Protection on Primary Chronic Lymphocytic Leukemia Cells after Treatment with BTK and MDM2 Pharmacological Inhibitors
por: Rimondi, Erika, et al.
Publicado: (2021)

Epidrug Repurposing: Discovering New Faces of Old Acquaintances in Cancer Therapy
por: Montalvo-Casimiro, Michel, et al.
Publicado: (2020)

Epidrugs in the Therapy of Central Nervous System Disorders: A Way to Drive on?
por: Gladkova, Marina G., et al.
Publicado: (2023)

Palmitic Acid Induced a Long-Lasting Lipotoxic Insult in Human Retinal Pigment Epithelial Cells, which Is Partially Counteracted by TRAIL
por: Sergi, Domenico, et al.
Publicado: (2022)

F13A1 Gene Variant (V34L) and Residual Circulating FXIIIA Levels Predict Short- and Long-Term Mortality in Acute Myocardial Infarction after Coronary Angioplasty
por: Ansani, Lucia, et al.
Publicado: (2018)

Cis-Segregation of c.1171C>T Stop Codon (p.R391*) in SERPINC1 Gene and c.1691G>A Transition (p.R506Q) in F5 Gene and Selected GWAS Multilocus Approach in Inherited Thrombophilia
por: Gemmati, Donato, et al.
Publicado: (2021)

Endothelial Cells Obtained from Patients Affected by Chronic Venous Disease Exhibit a Pro-Inflammatory Phenotype
por: Tisato, Veronica, et al.
Publicado: (2012)

Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model
por: Tisato, Veronica, et al.
Publicado: (2014)

UPF1 silenced cellular model systems for screening of read-through agents active on β(0)39 thalassemia point mutation
por: Salvatori, Francesca, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dc2g9dt4bh8vqn23okdf79828q