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Targeting NKG2DL with Bispecific NKG2D–CD16 and NKG2D–CD3 Fusion Proteins on Triple–Negative Breast Cancer

Triple–negative breast cancer (TNBC) is a particularly aggressive subtype of breast cancer with a poor response rate to conventional systemic treatment and high relapse rates. Members of the natural killer group 2D ligand (NKG2DL) family are expressed on cancer cells but are typically absent from he...

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Detalles Bibliográficos
Autores principales: Kaidun, Polina, Holzmayer, Samuel J., Greiner, Sarah M., Seller, Anna, Tegeler, Christian M., Hagelstein, Ilona, Mauermann, Jonas, Engler, Tobias, Koch, André, Hartkopf, Andreas D., Salih, Helmut R., Märklin, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487695/
https://www.ncbi.nlm.nih.gov/pubmed/37685962
http://dx.doi.org/10.3390/ijms241713156