Repeated Methamphetamine Administration Results in Axon Loss Prior to Somatic Loss of Substantia Nigra Pars Compacta and Locus Coeruleus Neurons in Male but Not Female Mice

Methamphetamine (meth) is a neurotoxic psychostimulant that increases monoamine oxidase (MAO)-dependent mitochondrial oxidant stress in axonal but not somatic compartments of substantia nigra pars compacta (SNc) and locus coeruleus (LC) neurons. Chronic meth administration results in the degeneratio...

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Detalles Bibliográficos
Autores principales: Pilski, Alexander, Graves, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487759/
https://www.ncbi.nlm.nih.gov/pubmed/37685846
http://dx.doi.org/10.3390/ijms241713039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487759/
https://www.ncbi.nlm.nih.gov/pubmed/37685846
http://dx.doi.org/10.3390/ijms241713039

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