Construction of a Matrix Cancer-Associated Fibroblast Signature Gene-Based Risk Prognostic Signature for Directing Immunotherapy in Patients with Breast Cancer Using Single-Cell Analysis and Machine Learning

Cancer-associated fibroblasts (CAFs) are heterogeneous constituents of the tumor microenvironment involved in the tumorigenesis, progression, and therapeutic responses of tumors. This study identified four distinct CAF subtypes of breast cancer (BRCA) using single-cell RNA sequencing (RNA-seq) data....

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Detalles Bibliográficos
Autores principales: Huang, Biaojie, Chen, Qiurui, Ye, Zhiyun, Zeng, Lin, Huang, Cuibing, Xie, Yuting, Zhang, Rongxin, Shen, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487765/
https://www.ncbi.nlm.nih.gov/pubmed/37685980
http://dx.doi.org/10.3390/ijms241713175

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