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Epigenetic Downregulation of Hsa-miR-193b-3p Increases Cyclin D1 Expression Level and Cell Proliferation in Human Meningiomas

Meningiomas are common intracranial tumors in adults. Abnormal microRNA (miRNA) expression plays a role in their pathogenesis. Change in miRNA expression level can be caused by impaired epigenetic regulation of miRNA-encoding genes. We found the genomic region covering the MIR193B gene to be DNA hyp...

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Detalles Bibliográficos
Autores principales: Kober, Paulina, Mossakowska, Beata Joanna, Rusetska, Natalia, Baluszek, Szymon, Grecka, Emilia, Konopiński, Ryszard, Matyja, Ewa, Oziębło, Artur, Mandat, Tomasz, Bujko, Mateusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487813/
https://www.ncbi.nlm.nih.gov/pubmed/37686289
http://dx.doi.org/10.3390/ijms241713483

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