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HLA Class I Expression Is Associated with DNA Damage and Immune Cell Infiltration into Dysplastic and Neoplastic Lesions in Ulcerative Colitis

Human leukocyte antigen class I (HLA-I) is considered a genetic pathogen for ulcerative colitis (UC). This study aimed to investigate the significance of DNA damage and HLA-I expression in infiltrating immune cells and immune checkpoint protein PD-L1 expression in dysplasia/colitic cancer (CC) and s...

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Detalles Bibliográficos
Autores principales: Okami, Haruka, Ozawa, Naoya, Sohda, Makoto, Yokobori, Takehiko, Osone, Katsuya, Erkhem-Ochir, Bilguun, Dorjkhorloo, Gendensuren, Shiraishi, Takuya, Okada, Takuhisa, Sano, Akihiko, Sakai, Makoto, Miyazaki, Tatsuya, Ogawa, Hiroomi, Yao, Takashi, Oike, Takahiro, Sato, Hiro, Shirabe, Ken, Shibata, Atsushi, Saeki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487850/
https://www.ncbi.nlm.nih.gov/pubmed/37686454
http://dx.doi.org/10.3390/ijms241713648