PD-L1 Downregulation and DNA Methylation Inhibition for Molecular Therapy against Cancer Stem Cells in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a heterogeneous cancer characterized by various cellular subtypes. This study investigates the potential of a combination strategy using immunotherapy and epigenetic reprogramming against HCC. We used a transgenic HCC mouse C57BL/6J-TG(ALB1HBV)44BRI/J to assess the...

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Detalles Bibliográficos
Autores principales: Sukowati, Caecilia, Cabral, Loraine Kay D., Anfuso, Beatrice, Dituri, Francesco, Negro, Roberto, Giannelli, Gianluigi, Tiribelli, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487900/
https://www.ncbi.nlm.nih.gov/pubmed/37686163
http://dx.doi.org/10.3390/ijms241713357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487900/
https://www.ncbi.nlm.nih.gov/pubmed/37686163
http://dx.doi.org/10.3390/ijms241713357

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