Advancement from Small Peptide Pharmaceuticals to Orally Active Piperazine-2,5-dion-Based Cyclopeptides

The oral delivery of peptide pharmaceuticals has long been a fundamental challenge in drug development. A new chemical platform was designed based on branched piperazine-2,5-diones for creating orally available biologically active peptidomimetics. The platform includes a bio-carrier with “built-in”...

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Detalles Bibliográficos
Autores principales: Deigin, Vladislav, Linkova, Natalia, Volpina, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487935/
https://www.ncbi.nlm.nih.gov/pubmed/37686336
http://dx.doi.org/10.3390/ijms241713534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487935/
https://www.ncbi.nlm.nih.gov/pubmed/37686336
http://dx.doi.org/10.3390/ijms241713534

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