ERK1/2-Dependent Phosphorylation of GABA(B1)(S867/T872), Controlled by CaMKIIβ, Is Required for GABA(B) Receptor Degradation under Physiological and Pathological Conditions

GABA(B) receptor-mediated inhibition is indispensable for maintaining a healthy neuronal excitation/inhibition balance. Many neurological diseases are associated with a disturbed excitation/inhibition balance and downregulation of GABA(B) receptors due to enhanced sorting of the receptors to lysosom...

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Detalles Bibliográficos
Autores principales: Bhat, Musadiq A., Grampp, Thomas, Benke, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488028/
https://www.ncbi.nlm.nih.gov/pubmed/37686242
http://dx.doi.org/10.3390/ijms241713436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488028/
https://www.ncbi.nlm.nih.gov/pubmed/37686242
http://dx.doi.org/10.3390/ijms241713436

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