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ERK1/2-Dependent Phosphorylation of GABA(B1)(S867/T872), Controlled by CaMKIIβ, Is Required for GABA(B) Receptor Degradation under Physiological and Pathological Conditions
GABA(B) receptor-mediated inhibition is indispensable for maintaining a healthy neuronal excitation/inhibition balance. Many neurological diseases are associated with a disturbed excitation/inhibition balance and downregulation of GABA(B) receptors due to enhanced sorting of the receptors to lysosom...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488028/ https://www.ncbi.nlm.nih.gov/pubmed/37686242 http://dx.doi.org/10.3390/ijms241713436 |