Cargando…
Uncovering the Role of Natural and Synthetic Small Molecules in Counteracting the Burden of α-Synuclein Aggregates and Related Toxicity in Different Models of Parkinson’s Disease
A proteostasis network represents a sophisticated cellular system that controls the whole process which leads to properly folded functional proteins. The imbalance of proteostasis determines a quantitative increase in misfolded proteins prone to aggregation and elicits the onset of different disease...
Autores principales: | Mohammed, Salihu, Russo, Isabella, Ramazzina, Ileana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488152/ https://www.ncbi.nlm.nih.gov/pubmed/37686175 http://dx.doi.org/10.3390/ijms241713370 |
Ejemplares similares
-
The Down-Regulation of Clusterin Expression Enhances the αSynuclein Aggregation Process
por: Lenzi, Chiara, et al.
Publicado: (2020) -
Synuclein Family Members Prevent Membrane Damage by Counteracting α-Synuclein Aggregation
por: Scheibe, Christian, et al.
Publicado: (2021) -
Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease
por: Emin, Derya, et al.
Publicado: (2022) -
Models of α-synuclein aggregation in Parkinson’s disease
por: Giráldez-Pérez, Rosa María, et al.
Publicado: (2014) -
Sumoylation inhibits α-synuclein aggregation and toxicity
por: Krumova, Petranka, et al.
Publicado: (2011)