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ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes

The human leukocyte antigen (HLA)-B*27 family of alleles is strongly associated with ankylosing spondylitis (AS), a chronic inflammatory disorder affecting the axial and peripheral joints, yet some HLA-B*27 variants not associated with AS have been shown. Since no major differences in the ligandome...

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Detalles Bibliográficos
Autores principales: Tedeschi, Valentina, Paldino, Giorgia, Alba, Josephine, Molteni, Emanuele, Paladini, Fabiana, Scrivo, Rossana, Congia, Mattia, Cauli, Alberto, Caccavale, Rosalba, Paroli, Marino, Di Franco, Manuela, Tuosto, Loretta, Sorrentino, Rosa, D’Abramo, Marco, Fiorillo, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488187/
https://www.ncbi.nlm.nih.gov/pubmed/37686141
http://dx.doi.org/10.3390/ijms241713335