Study of Nuclear Reactions in Therapy of Tumors with Proton Beams

This paper presents an assessment of nuclear reaction yields of protons, [Formula: see text]-particles, and neutrons in human tissue-equivalentmaterial in proton therapy using a simulation with Geant 4. In this study, we also check an enhancement of nuclear reactions due to the presence of Bi, Au, [Formula: see text] B, and [Formula: see text] B radiosensitizer nanoparticles. We demonstrate that a proton beam induces a noticeable amount of nuclear reactions in the tissue. Nevertheless, the enhancement of nuclear reaction products due to radiosensitizer nanoparticles is found to be negligible.