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Advances in the Relationship between Respiratory Viruses and Asthma
Several studies have reported that viral infection is closely associated with the onset, progression, and exacerbation of asthma. The purpose of this review is to summarize the role that viral infections have in the pathogenesis of asthma onset and exacerbations, as well as discuss interrelated prot...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488270/ https://www.ncbi.nlm.nih.gov/pubmed/37685567 http://dx.doi.org/10.3390/jcm12175501 |
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author | Romero-Tapia, Sergio de Jesús Guzmán Priego, Crystell Guadalupe Del-Río-Navarro, Blanca E. Sánchez-Solis, Manuel |
author_facet | Romero-Tapia, Sergio de Jesús Guzmán Priego, Crystell Guadalupe Del-Río-Navarro, Blanca E. Sánchez-Solis, Manuel |
author_sort | Romero-Tapia, Sergio de Jesús |
collection | PubMed |
description | Several studies have reported that viral infection is closely associated with the onset, progression, and exacerbation of asthma. The purpose of this review is to summarize the role that viral infections have in the pathogenesis of asthma onset and exacerbations, as well as discuss interrelated protective and risk factors of asthma and current treatment options. Furthermore, we present current knowledge of the innate immunological pathways driving host defense, including changes in the epithelial barrier. In addition, we highlight the importance of the genetics and epigenetics of asthma and virus susceptibility. Moreover, the involvement of virus etiology from bronchiolitis and childhood wheezing to asthma is described. The characterization and mechanisms of action of the respiratory viruses most frequently related to asthma are mentioned. |
format | Online Article Text |
id | pubmed-10488270 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104882702023-09-09 Advances in the Relationship between Respiratory Viruses and Asthma Romero-Tapia, Sergio de Jesús Guzmán Priego, Crystell Guadalupe Del-Río-Navarro, Blanca E. Sánchez-Solis, Manuel J Clin Med Review Several studies have reported that viral infection is closely associated with the onset, progression, and exacerbation of asthma. The purpose of this review is to summarize the role that viral infections have in the pathogenesis of asthma onset and exacerbations, as well as discuss interrelated protective and risk factors of asthma and current treatment options. Furthermore, we present current knowledge of the innate immunological pathways driving host defense, including changes in the epithelial barrier. In addition, we highlight the importance of the genetics and epigenetics of asthma and virus susceptibility. Moreover, the involvement of virus etiology from bronchiolitis and childhood wheezing to asthma is described. The characterization and mechanisms of action of the respiratory viruses most frequently related to asthma are mentioned. MDPI 2023-08-24 /pmc/articles/PMC10488270/ /pubmed/37685567 http://dx.doi.org/10.3390/jcm12175501 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Romero-Tapia, Sergio de Jesús Guzmán Priego, Crystell Guadalupe Del-Río-Navarro, Blanca E. Sánchez-Solis, Manuel Advances in the Relationship between Respiratory Viruses and Asthma |
title | Advances in the Relationship between Respiratory Viruses and Asthma |
title_full | Advances in the Relationship between Respiratory Viruses and Asthma |
title_fullStr | Advances in the Relationship between Respiratory Viruses and Asthma |
title_full_unstemmed | Advances in the Relationship between Respiratory Viruses and Asthma |
title_short | Advances in the Relationship between Respiratory Viruses and Asthma |
title_sort | advances in the relationship between respiratory viruses and asthma |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488270/ https://www.ncbi.nlm.nih.gov/pubmed/37685567 http://dx.doi.org/10.3390/jcm12175501 |
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