Cargando…

Advances in the Relationship between Respiratory Viruses and Asthma

Several studies have reported that viral infection is closely associated with the onset, progression, and exacerbation of asthma. The purpose of this review is to summarize the role that viral infections have in the pathogenesis of asthma onset and exacerbations, as well as discuss interrelated prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Romero-Tapia, Sergio de Jesús, Guzmán Priego, Crystell Guadalupe, Del-Río-Navarro, Blanca E., Sánchez-Solis, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488270/
https://www.ncbi.nlm.nih.gov/pubmed/37685567
http://dx.doi.org/10.3390/jcm12175501
_version_ 1785103439013871616
author Romero-Tapia, Sergio de Jesús
Guzmán Priego, Crystell Guadalupe
Del-Río-Navarro, Blanca E.
Sánchez-Solis, Manuel
author_facet Romero-Tapia, Sergio de Jesús
Guzmán Priego, Crystell Guadalupe
Del-Río-Navarro, Blanca E.
Sánchez-Solis, Manuel
author_sort Romero-Tapia, Sergio de Jesús
collection PubMed
description Several studies have reported that viral infection is closely associated with the onset, progression, and exacerbation of asthma. The purpose of this review is to summarize the role that viral infections have in the pathogenesis of asthma onset and exacerbations, as well as discuss interrelated protective and risk factors of asthma and current treatment options. Furthermore, we present current knowledge of the innate immunological pathways driving host defense, including changes in the epithelial barrier. In addition, we highlight the importance of the genetics and epigenetics of asthma and virus susceptibility. Moreover, the involvement of virus etiology from bronchiolitis and childhood wheezing to asthma is described. The characterization and mechanisms of action of the respiratory viruses most frequently related to asthma are mentioned.
format Online
Article
Text
id pubmed-10488270
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104882702023-09-09 Advances in the Relationship between Respiratory Viruses and Asthma Romero-Tapia, Sergio de Jesús Guzmán Priego, Crystell Guadalupe Del-Río-Navarro, Blanca E. Sánchez-Solis, Manuel J Clin Med Review Several studies have reported that viral infection is closely associated with the onset, progression, and exacerbation of asthma. The purpose of this review is to summarize the role that viral infections have in the pathogenesis of asthma onset and exacerbations, as well as discuss interrelated protective and risk factors of asthma and current treatment options. Furthermore, we present current knowledge of the innate immunological pathways driving host defense, including changes in the epithelial barrier. In addition, we highlight the importance of the genetics and epigenetics of asthma and virus susceptibility. Moreover, the involvement of virus etiology from bronchiolitis and childhood wheezing to asthma is described. The characterization and mechanisms of action of the respiratory viruses most frequently related to asthma are mentioned. MDPI 2023-08-24 /pmc/articles/PMC10488270/ /pubmed/37685567 http://dx.doi.org/10.3390/jcm12175501 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Romero-Tapia, Sergio de Jesús
Guzmán Priego, Crystell Guadalupe
Del-Río-Navarro, Blanca E.
Sánchez-Solis, Manuel
Advances in the Relationship between Respiratory Viruses and Asthma
title Advances in the Relationship between Respiratory Viruses and Asthma
title_full Advances in the Relationship between Respiratory Viruses and Asthma
title_fullStr Advances in the Relationship between Respiratory Viruses and Asthma
title_full_unstemmed Advances in the Relationship between Respiratory Viruses and Asthma
title_short Advances in the Relationship between Respiratory Viruses and Asthma
title_sort advances in the relationship between respiratory viruses and asthma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488270/
https://www.ncbi.nlm.nih.gov/pubmed/37685567
http://dx.doi.org/10.3390/jcm12175501
work_keys_str_mv AT romerotapiasergiodejesus advancesintherelationshipbetweenrespiratoryvirusesandasthma
AT guzmanpriegocrystellguadalupe advancesintherelationshipbetweenrespiratoryvirusesandasthma
AT delrionavarroblancae advancesintherelationshipbetweenrespiratoryvirusesandasthma
AT sanchezsolismanuel advancesintherelationshipbetweenrespiratoryvirusesandasthma