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Human Bone-Marrow-Derived Stem-Cell-Seeded 3D Chitosan–Gelatin–Genipin Scaffolds Show Enhanced Extracellular Matrix Mineralization When Cultured under a Perfusion Flow in Osteogenic Medium

Tissue-engineered bone tissue grafts are a promising alternative to the more conventional use of natural donor bone grafts. However, choosing an appropriate biomaterial/scaffold to sustain cell survival, proliferation, and differentiation in a 3D environment remains one of the most critical issues i...

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Detalles Bibliográficos
Autores principales: Boretti, Gabriele, Giordano, Emanuele, Ionita, Mariana, Vlasceanu, George Mihail, Sigurjónsson, Ólafur Eysteinn, Gargiulo, Paolo, Lovecchio, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488422/
https://www.ncbi.nlm.nih.gov/pubmed/37687590
http://dx.doi.org/10.3390/ma16175898