Cargando…

APOE ε4 Gene Carriers Demonstrate Reduced Retinal Capillary Densities in Asymptomatic Older Adults

Early identification of Apolipoprotein E (APOE)-related microvascular pathology will help to study the microangiopathic contribution to Alzheimer’s disease and provide a therapeutic target for early intervention. To evaluate the differences in retinal microvasculature parameters between APOE ε4 carr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ziyi, Kwapong, William Robert, Cao, Le, Feng, Zijuan, Wu, Bo, Liu, Junfeng, Zhang, Shuting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488535/ https://www.ncbi.nlm.nih.gov/pubmed/37685715 http://dx.doi.org/10.3390/jcm12175649

Ejemplares similares

Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers
por: Elahi, Fanny M., et al.
Publicado: (2021)

Anxiety correlates with cortical surface area in subjective cognitive decline: APOE ε4 carriers versus APOE ε4 non-carriers
por: Sun, Yu, et al.
Publicado: (2019)

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles
por: Walker, Rosie M., et al.
Publicado: (2021)

Sex and APOE: A memory advantage in male APOE ε4 carriers in midlife
por: Zokaei, Nahid, et al.
Publicado: (2017)

Differences in resting-state brain networks and gray matter between APOE ε2 and APOE ε4 carriers in non-dementia elderly
por: Wang, Zhiyuan, et al.
Publicado: (2023)

Bioenergetic and inflammatory systemic phenotypes in Alzheimer’s disease APOE ε4‐carriers
por: Wilkins, Heather M., et al.
Publicado: (2021)

A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer’s Disease
por: Jiang, Shan, et al.
Publicado: (2016)

Association of APOE Serum Levels and APOE ε2, ε3, and ε4 Alleles with Optic Neuritis
por: Momkute, Liucija, et al.
Publicado: (2022)

Impaired memory-guided attention in asymptomatic APOE4 carriers
por: Zimmermann, Jacqueline, et al.
Publicado: (2019)

Length of Carotid Plaque Impacts Retinal Microvascular Densities of Carotid Artery Stenosis Patients
por: Cao, Le, et al.
Publicado: (2023)

APOEε4 and slow wave sleep in older adults
por: Tranah, Gregory J., et al.
Publicado: (2018)

Decreased plasma C‐reactive protein levels in APOE ε4 allele carriers
por: Martiskainen, Henna, et al.
Publicado: (2018)

Short-term memory advantage for brief durations in human APOE ε4 carriers
por: Zokaei, Nahid, et al.
Publicado: (2020)

Superior short-term memory in APOE ε2 carriers across the age range
por: Zokaei, Nahid, et al.
Publicado: (2021)

APOE-ε4 Carrier Status and Gut Microbiota Dysbiosis in Patients With Alzheimer Disease
por: Hou, Min, et al.
Publicado: (2021)

Learning deficit in cognitively normal APOE ε4 carriers with LOW β‐amyloid
por: Lim, Yen Ying, et al.
Publicado: (2021)

Risk of dementia in APOE ε4 carriers is mitigated by a polygenic risk score
por: Ebenau, Jarith L., et al.
Publicado: (2021)

The Effects of rs405509 on APOEε4 Non-carriers in Non-demented Aging
por: Wu, Dongpeng, et al.
Publicado: (2021)

Differential association of cerebral blood flow and anisocytosis in APOE ε4 carriers at midlife
por: Dounavi, Maria-Eleni, et al.
Publicado: (2023)

Association of Homocysteine Levels With Medial Temporal Lobe Atrophy Among Carriers and Non-carriers of APOE ε4 in MCI Subjects
por: Ma, Jun, et al.
Publicado: (2022)

Association of retinal thickness and microvasculature with cognitive performance and brain volumes in elderly adults
por: Wang, Ruilin, et al.
Publicado: (2022)

Platelet cytochrome oxidase and citrate synthase activities in APOE ε4 carrier and non-carrier Alzheimer's disease patients
por: Wilkins, Heather M., et al.
Publicado: (2017)

Accelerated Cell Aging in Female APOE-ε4 Carriers: Implications for Hormone Therapy Use
por: Jacobs, Emily G., et al.
Publicado: (2013)

Corrigendum: The Effects of rs405509 on APOEε4 Non-carriers in Non-demented Aging
por: Wu, Dongpeng, et al.
Publicado: (2022)

Reduced Superficial Capillary Density in Cerebral Infarction Is Inversely Correlated With the NIHSS Score
por: Kwapong, William Robert, et al.
Publicado: (2021)

Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia
por: Salvadó, Gemma, et al.
Publicado: (2021)

Alterations in dorsal and ventral posterior cingulate connectivity in APOE ε4 carriers at risk of Alzheimer's disease
por: Kerestes, Rebecca, et al.
Publicado: (2015)

Verbal memory improvement in first-episode psychosis APOE-ε4 carriers: a pleiotropic effect?
por: Vila-Rodriguez, Fidel, et al.
Publicado: (2017)

CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers
por: Ahmad, Shahzad, et al.
Publicado: (2020)

Increased apolipoprotein E and decreased TNF‐α in the cerebrospinal fluid of nondemented APOE‐ε4 carriers
por: Sasayama, Daimei, et al.
Publicado: (2020)

Evidence of cerebral hemodynamic dysregulation in middle-aged APOE ε4 carriers: The PREVENT-Dementia study
por: Dounavi, Maria-Eleni, et al.
Publicado: (2021)

Memory precision of object-location binding is unimpaired in APOE ε4-carriers with spatial navigation deficits
por: Gellersen, Helena M, et al.
Publicado: (2021)

OBJECTIVELY MEASURED PHYSICAL ACTIVITY PATTERNS OVER 24-HOURS BY APOE-Ε4 CARRIER STATUS
por: Wanigatunga, Amal, et al.
Publicado: (2022)

Association between ApoE ε4 Carrier Status and Cardiovascular Risk Factors on Mild Cognitive Impairment among Mexican Older Adults
por: Aguilar-Navarro, Sara G., et al.
Publicado: (2021)

Lower retinal capillary density in minimal cognitive impairment among older Latinx adults
por: Ashimatey, Bright S., et al.
Publicado: (2020)

Impact of sex and APOE ε4 on age-related cerebral perfusion trajectories in cognitively asymptomatic middle-aged and older adults: A longitudinal study
por: Wang, Rui, et al.
Publicado: (2021)

The Association of APOE ε4 Allele with Retinal Layer Thickness and Microvasculature in Older Adults: Optic Nerve Decline and Cognitive Change Study
por: Sheriff, Samran, et al.
Publicado: (2023)

Longitudinal association between hippocampus atrophy and episodic‐memory decline in non‐demented APOE ε4 carriers
por: Gorbach, Tetiana, et al.
Publicado: (2020)

The MAPT H1 Haplotype Is a Risk Factor for Alzheimer’s Disease in APOE ε4 Non-carriers
por: Sánchez-Juan, Pascual, et al.
Publicado: (2019)

Novel Alzheimer’s disease risk variants identified based on whole-genome sequencing of APOE ε4 carriers
por: Park, Jong-Ho, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ee8fq0g1751aqd231gs5aj4831