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Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract

Hydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed mat...

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Autores principales: Kędzierska, Magdalena, Sala, Katarzyna, Bańkosz, Magdalena, Wroniak, Dominika, Gajda, Paweł, Potemski, Piotr, Tyliszczak, Bożena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488629/
https://www.ncbi.nlm.nih.gov/pubmed/37687730
http://dx.doi.org/10.3390/ma16176037
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author Kędzierska, Magdalena
Sala, Katarzyna
Bańkosz, Magdalena
Wroniak, Dominika
Gajda, Paweł
Potemski, Piotr
Tyliszczak, Bożena
author_facet Kędzierska, Magdalena
Sala, Katarzyna
Bańkosz, Magdalena
Wroniak, Dominika
Gajda, Paweł
Potemski, Piotr
Tyliszczak, Bożena
author_sort Kędzierska, Magdalena
collection PubMed
description Hydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed materials were obtained in the field of UV radiation. The correlation between the amount of photoinitiator used and the physicochemical properties and surface morphology of the obtained materials was investigated. In addition, the hydrogels have been incorporated with wild rose extract, which is characterized by antioxidant and anti-inflammatory effects. The analysis of the sorption capacity confirmed that the obtained material is able to absorb significant amounts of incubation fluids, which, in terms of application, will enable the absorption of exudate from the wound. The highest stability of materials was noted for hydrogels obtained with the use of intermediate amounts of photoinitiator, i.e., 50 µL and 70 µL. In the case of using 20 µL or 100 µL, the photopolymerization process did not proceed properly and the obtained material was characterized by a lack of homogeneity and high brittleness. With the increase in the amount of photoinitiator, an increase in the surface roughness of hydrogel materials was confirmed. In turn, spectroscopic analysis ruled out the degradation of materials in incubation fluids, indicating the potential for their use in biomedical applications.
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spelling pubmed-104886292023-09-09 Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract Kędzierska, Magdalena Sala, Katarzyna Bańkosz, Magdalena Wroniak, Dominika Gajda, Paweł Potemski, Piotr Tyliszczak, Bożena Materials (Basel) Article Hydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed materials were obtained in the field of UV radiation. The correlation between the amount of photoinitiator used and the physicochemical properties and surface morphology of the obtained materials was investigated. In addition, the hydrogels have been incorporated with wild rose extract, which is characterized by antioxidant and anti-inflammatory effects. The analysis of the sorption capacity confirmed that the obtained material is able to absorb significant amounts of incubation fluids, which, in terms of application, will enable the absorption of exudate from the wound. The highest stability of materials was noted for hydrogels obtained with the use of intermediate amounts of photoinitiator, i.e., 50 µL and 70 µL. In the case of using 20 µL or 100 µL, the photopolymerization process did not proceed properly and the obtained material was characterized by a lack of homogeneity and high brittleness. With the increase in the amount of photoinitiator, an increase in the surface roughness of hydrogel materials was confirmed. In turn, spectroscopic analysis ruled out the degradation of materials in incubation fluids, indicating the potential for their use in biomedical applications. MDPI 2023-09-02 /pmc/articles/PMC10488629/ /pubmed/37687730 http://dx.doi.org/10.3390/ma16176037 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kędzierska, Magdalena
Sala, Katarzyna
Bańkosz, Magdalena
Wroniak, Dominika
Gajda, Paweł
Potemski, Piotr
Tyliszczak, Bożena
Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_full Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_fullStr Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_full_unstemmed Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_short Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_sort investigation of physicochemical properties and surface morphology of hydrogel materials incorporating rosehip extract
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488629/
https://www.ncbi.nlm.nih.gov/pubmed/37687730
http://dx.doi.org/10.3390/ma16176037
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