Cargando…
Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
Hydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed mat...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488629/ https://www.ncbi.nlm.nih.gov/pubmed/37687730 http://dx.doi.org/10.3390/ma16176037 |
_version_ | 1785103521211744256 |
---|---|
author | Kędzierska, Magdalena Sala, Katarzyna Bańkosz, Magdalena Wroniak, Dominika Gajda, Paweł Potemski, Piotr Tyliszczak, Bożena |
author_facet | Kędzierska, Magdalena Sala, Katarzyna Bańkosz, Magdalena Wroniak, Dominika Gajda, Paweł Potemski, Piotr Tyliszczak, Bożena |
author_sort | Kędzierska, Magdalena |
collection | PubMed |
description | Hydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed materials were obtained in the field of UV radiation. The correlation between the amount of photoinitiator used and the physicochemical properties and surface morphology of the obtained materials was investigated. In addition, the hydrogels have been incorporated with wild rose extract, which is characterized by antioxidant and anti-inflammatory effects. The analysis of the sorption capacity confirmed that the obtained material is able to absorb significant amounts of incubation fluids, which, in terms of application, will enable the absorption of exudate from the wound. The highest stability of materials was noted for hydrogels obtained with the use of intermediate amounts of photoinitiator, i.e., 50 µL and 70 µL. In the case of using 20 µL or 100 µL, the photopolymerization process did not proceed properly and the obtained material was characterized by a lack of homogeneity and high brittleness. With the increase in the amount of photoinitiator, an increase in the surface roughness of hydrogel materials was confirmed. In turn, spectroscopic analysis ruled out the degradation of materials in incubation fluids, indicating the potential for their use in biomedical applications. |
format | Online Article Text |
id | pubmed-10488629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104886292023-09-09 Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract Kędzierska, Magdalena Sala, Katarzyna Bańkosz, Magdalena Wroniak, Dominika Gajda, Paweł Potemski, Piotr Tyliszczak, Bożena Materials (Basel) Article Hydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed materials were obtained in the field of UV radiation. The correlation between the amount of photoinitiator used and the physicochemical properties and surface morphology of the obtained materials was investigated. In addition, the hydrogels have been incorporated with wild rose extract, which is characterized by antioxidant and anti-inflammatory effects. The analysis of the sorption capacity confirmed that the obtained material is able to absorb significant amounts of incubation fluids, which, in terms of application, will enable the absorption of exudate from the wound. The highest stability of materials was noted for hydrogels obtained with the use of intermediate amounts of photoinitiator, i.e., 50 µL and 70 µL. In the case of using 20 µL or 100 µL, the photopolymerization process did not proceed properly and the obtained material was characterized by a lack of homogeneity and high brittleness. With the increase in the amount of photoinitiator, an increase in the surface roughness of hydrogel materials was confirmed. In turn, spectroscopic analysis ruled out the degradation of materials in incubation fluids, indicating the potential for their use in biomedical applications. MDPI 2023-09-02 /pmc/articles/PMC10488629/ /pubmed/37687730 http://dx.doi.org/10.3390/ma16176037 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kędzierska, Magdalena Sala, Katarzyna Bańkosz, Magdalena Wroniak, Dominika Gajda, Paweł Potemski, Piotr Tyliszczak, Bożena Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract |
title | Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract |
title_full | Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract |
title_fullStr | Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract |
title_full_unstemmed | Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract |
title_short | Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract |
title_sort | investigation of physicochemical properties and surface morphology of hydrogel materials incorporating rosehip extract |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10488629/ https://www.ncbi.nlm.nih.gov/pubmed/37687730 http://dx.doi.org/10.3390/ma16176037 |
work_keys_str_mv | AT kedzierskamagdalena investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract AT salakatarzyna investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract AT bankoszmagdalena investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract AT wroniakdominika investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract AT gajdapaweł investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract AT potemskipiotr investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract AT tyliszczakbozena investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract |