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Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy

Skin cancer is a condition characterized by the abnormal growth of skin cells, primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Different types of skin cancer include melanoma, basal cell carcinoma, and squamous cell carcinoma. Despite...

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Autores principales: Baloghová, Janette, Michalková, Radka, Baranová, Zuzana, Mojžišová, Gabriela, Fedáková, Zuzana, Mojžiš, Ján
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489044/
https://www.ncbi.nlm.nih.gov/pubmed/37687080
http://dx.doi.org/10.3390/molecules28176251
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author Baloghová, Janette
Michalková, Radka
Baranová, Zuzana
Mojžišová, Gabriela
Fedáková, Zuzana
Mojžiš, Ján
author_facet Baloghová, Janette
Michalková, Radka
Baranová, Zuzana
Mojžišová, Gabriela
Fedáková, Zuzana
Mojžiš, Ján
author_sort Baloghová, Janette
collection PubMed
description Skin cancer is a condition characterized by the abnormal growth of skin cells, primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Different types of skin cancer include melanoma, basal cell carcinoma, and squamous cell carcinoma. Despite the advancements in targeted therapies, there is still a need for a safer, highly efficient approach to preventing and treating cutaneous malignancies. Spices have a rich history dating back thousands of years and are renowned for their ability to enhance the flavor, taste, and color of food. Derived from various plant parts like seeds, fruits, bark, roots, or flowers, spices are important culinary ingredients. However, their value extends beyond the culinary realm. Some spices contain bioactive compounds, including phenolic compounds, which are known for their significant biological effects. These compounds have attracted attention in scientific research due to their potential health benefits, including their possible role in disease prevention and treatment, such as cancer. This review focuses on examining the potential of spice-derived phenolic compounds as preventive or therapeutic agents for managing skin cancers. By compiling and analyzing the available knowledge, this review aims to provide insights that can guide future research in identifying new anticancer phytochemicals and uncovering additional mechanisms for combating skin cancer.
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spelling pubmed-104890442023-09-09 Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy Baloghová, Janette Michalková, Radka Baranová, Zuzana Mojžišová, Gabriela Fedáková, Zuzana Mojžiš, Ján Molecules Review Skin cancer is a condition characterized by the abnormal growth of skin cells, primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Different types of skin cancer include melanoma, basal cell carcinoma, and squamous cell carcinoma. Despite the advancements in targeted therapies, there is still a need for a safer, highly efficient approach to preventing and treating cutaneous malignancies. Spices have a rich history dating back thousands of years and are renowned for their ability to enhance the flavor, taste, and color of food. Derived from various plant parts like seeds, fruits, bark, roots, or flowers, spices are important culinary ingredients. However, their value extends beyond the culinary realm. Some spices contain bioactive compounds, including phenolic compounds, which are known for their significant biological effects. These compounds have attracted attention in scientific research due to their potential health benefits, including their possible role in disease prevention and treatment, such as cancer. This review focuses on examining the potential of spice-derived phenolic compounds as preventive or therapeutic agents for managing skin cancers. By compiling and analyzing the available knowledge, this review aims to provide insights that can guide future research in identifying new anticancer phytochemicals and uncovering additional mechanisms for combating skin cancer. MDPI 2023-08-25 /pmc/articles/PMC10489044/ /pubmed/37687080 http://dx.doi.org/10.3390/molecules28176251 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Baloghová, Janette
Michalková, Radka
Baranová, Zuzana
Mojžišová, Gabriela
Fedáková, Zuzana
Mojžiš, Ján
Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy
title Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy
title_full Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy
title_fullStr Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy
title_full_unstemmed Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy
title_short Spice-Derived Phenolic Compounds: Potential for Skin Cancer Prevention and Therapy
title_sort spice-derived phenolic compounds: potential for skin cancer prevention and therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489044/
https://www.ncbi.nlm.nih.gov/pubmed/37687080
http://dx.doi.org/10.3390/molecules28176251
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