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Effect of platelet content on occurrence and prognosis of distal radius fracture

Fractures of the distal radius are a common fracture with an increasing incidence. However, the underlying factors for distal radius fractures (DRFs) remain unclear. A total of 123 patients with distal radial fractures were recruited. To document clinical and follow-up data, and measure the levels o...

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Autores principales: Ding, Danyang, Zhu, Hao, Zheng, Meiliang, Kang, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489189/
https://www.ncbi.nlm.nih.gov/pubmed/37682171
http://dx.doi.org/10.1097/MD.0000000000035043
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author Ding, Danyang
Zhu, Hao
Zheng, Meiliang
Kang, Chunbo
author_facet Ding, Danyang
Zhu, Hao
Zheng, Meiliang
Kang, Chunbo
author_sort Ding, Danyang
collection PubMed
description Fractures of the distal radius are a common fracture with an increasing incidence. However, the underlying factors for distal radius fractures (DRFs) remain unclear. A total of 123 patients with distal radial fractures were recruited. To document clinical and follow-up data, and measure the levels of white blood cells, hemoglobin, platelets, and red blood cells in the bloodstream for qualitative observation of their expression effects within the human body, specifically assessing whether the magnitudes of these indicators are associated with potential factors influencing DRF. Pearson chi-square test and Spearman correlation were used to analyze the relationship between DRF and related parameters. Univariate and multivariate logistic regression and multivariate Cox proportional risk regression were used for further analysis. Pearson chi-square test and Spearman correlation analysis showed a significant correlation between platelet and red blood cell levels and the occurrence of DRFs. Univariate logistic regression analysis demonstrated a significant correlation between platelet count (OR [odds ratio] = 6.286, 95% CI [confidence interval]: 2.862–13.808, P < .001) and red blood cell count (OR = 2.780, 95% CI: 1.322–5.843, P = .007) with DRFs. Increasing levels of both indicators were associated with a higher susceptibility to DRFs. Multivariate logistic regression showed that platelets (OR = 6.344, 95% CI: 2.709–14.855, P < .001) were significantly associated with DRFs. Multivariate Cox regression analysis showed sex (HR [hazard ratio] = 0.596, 95% CI: 0.381–0.931, P = .023) and platelet (HR = 3.721, 95% CI: 2.364–5.855, P < .001) were significantly associated with maintenance time from recovery to recurrence (MTRR) of DRFs. In other words, the platelet content in the body of different genders is different, and the MTRR of DRF is different. Platelets were significantly associated with DRFs. The higher the platelet count, the higher the risk of DRF and the shorter the time of DRF recurrence.
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spelling pubmed-104891892023-09-09 Effect of platelet content on occurrence and prognosis of distal radius fracture Ding, Danyang Zhu, Hao Zheng, Meiliang Kang, Chunbo Medicine (Baltimore) 3700 Fractures of the distal radius are a common fracture with an increasing incidence. However, the underlying factors for distal radius fractures (DRFs) remain unclear. A total of 123 patients with distal radial fractures were recruited. To document clinical and follow-up data, and measure the levels of white blood cells, hemoglobin, platelets, and red blood cells in the bloodstream for qualitative observation of their expression effects within the human body, specifically assessing whether the magnitudes of these indicators are associated with potential factors influencing DRF. Pearson chi-square test and Spearman correlation were used to analyze the relationship between DRF and related parameters. Univariate and multivariate logistic regression and multivariate Cox proportional risk regression were used for further analysis. Pearson chi-square test and Spearman correlation analysis showed a significant correlation between platelet and red blood cell levels and the occurrence of DRFs. Univariate logistic regression analysis demonstrated a significant correlation between platelet count (OR [odds ratio] = 6.286, 95% CI [confidence interval]: 2.862–13.808, P < .001) and red blood cell count (OR = 2.780, 95% CI: 1.322–5.843, P = .007) with DRFs. Increasing levels of both indicators were associated with a higher susceptibility to DRFs. Multivariate logistic regression showed that platelets (OR = 6.344, 95% CI: 2.709–14.855, P < .001) were significantly associated with DRFs. Multivariate Cox regression analysis showed sex (HR [hazard ratio] = 0.596, 95% CI: 0.381–0.931, P = .023) and platelet (HR = 3.721, 95% CI: 2.364–5.855, P < .001) were significantly associated with maintenance time from recovery to recurrence (MTRR) of DRFs. In other words, the platelet content in the body of different genders is different, and the MTRR of DRF is different. Platelets were significantly associated with DRFs. The higher the platelet count, the higher the risk of DRF and the shorter the time of DRF recurrence. Lippincott Williams & Wilkins 2023-09-08 /pmc/articles/PMC10489189/ /pubmed/37682171 http://dx.doi.org/10.1097/MD.0000000000035043 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 3700
Ding, Danyang
Zhu, Hao
Zheng, Meiliang
Kang, Chunbo
Effect of platelet content on occurrence and prognosis of distal radius fracture
title Effect of platelet content on occurrence and prognosis of distal radius fracture
title_full Effect of platelet content on occurrence and prognosis of distal radius fracture
title_fullStr Effect of platelet content on occurrence and prognosis of distal radius fracture
title_full_unstemmed Effect of platelet content on occurrence and prognosis of distal radius fracture
title_short Effect of platelet content on occurrence and prognosis of distal radius fracture
title_sort effect of platelet content on occurrence and prognosis of distal radius fracture
topic 3700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489189/
https://www.ncbi.nlm.nih.gov/pubmed/37682171
http://dx.doi.org/10.1097/MD.0000000000035043
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