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Tinker, Tailor, Soldier, Spy: The Diverse Roles That Fluorine Can Play within Amino Acid Side Chains

Side chain-fluorinated amino acids are useful tools in medicinal chemistry and protein science. In this review, we outline some general strategies for incorporating fluorine atom(s) into amino acid side chains and for elaborating such building blocks into more complex fluorinated peptides and protei...

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Detalles Bibliográficos
Autores principales: Miles, Samantha A., Nillama, Joshua Andrew, Hunter, Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489206/
https://www.ncbi.nlm.nih.gov/pubmed/37687021
http://dx.doi.org/10.3390/molecules28176192