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Pelviureteric junction obstruction in adults: A systematic review of the literature

BACKGROUND: Pelviureteric junction obstruction (PUJO) is a common urological disorder that can present at any stage of life. The underlying etiology in children has been well studied; however, a gap exists in the literature for the adult population. Herein, we performed a systematic review of the li...

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Autores principales: O'Sullivan, Niall J., Anderson, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489243/
https://www.ncbi.nlm.nih.gov/pubmed/37691990
http://dx.doi.org/10.1097/CU9.0000000000000154
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author O'Sullivan, Niall J.
Anderson, Steven
author_facet O'Sullivan, Niall J.
Anderson, Steven
author_sort O'Sullivan, Niall J.
collection PubMed
description BACKGROUND: Pelviureteric junction obstruction (PUJO) is a common urological disorder that can present at any stage of life. The underlying etiology in children has been well studied; however, a gap exists in the literature for the adult population. Herein, we performed a systematic review of the literature to evaluate the current evidence on the underlying etiologies of adult patients presenting with PUJO. MATERIALS AND METHODS: Four electronic databases were searched for relevant studies assessing the underlying etiologies of pelviureteric junction obstruction in adults. Studies were assessed for eligibility based on predefined inclusion and exclusion criteria, and a critical appraisal of methodological quality and risk of bias was performed. Finally, qualitative and quantitative data analyses were performed. RESULTS: Twelve studies comprising a total of 513 patients with radiologically confirmed PUJO met the inclusion criteria and were included in our analysis. The most common finding was crossing vessels, which were observed in 50.5% of patients, followed by intrinsic ureteral stenosis (27.1%), adhesions (15.3%), and high insertion of the ureter (10.1%). CONCLUSIONS: The underlying etiologies of PUJO in adults remain unclear. This study indicated that obstruction secondary to crossing vessels is the most common cause of obstruction in adults and occurs more frequently than in the pediatric population.
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spelling pubmed-104892432023-09-09 Pelviureteric junction obstruction in adults: A systematic review of the literature O'Sullivan, Niall J. Anderson, Steven Curr Urol Reviews BACKGROUND: Pelviureteric junction obstruction (PUJO) is a common urological disorder that can present at any stage of life. The underlying etiology in children has been well studied; however, a gap exists in the literature for the adult population. Herein, we performed a systematic review of the literature to evaluate the current evidence on the underlying etiologies of adult patients presenting with PUJO. MATERIALS AND METHODS: Four electronic databases were searched for relevant studies assessing the underlying etiologies of pelviureteric junction obstruction in adults. Studies were assessed for eligibility based on predefined inclusion and exclusion criteria, and a critical appraisal of methodological quality and risk of bias was performed. Finally, qualitative and quantitative data analyses were performed. RESULTS: Twelve studies comprising a total of 513 patients with radiologically confirmed PUJO met the inclusion criteria and were included in our analysis. The most common finding was crossing vessels, which were observed in 50.5% of patients, followed by intrinsic ureteral stenosis (27.1%), adhesions (15.3%), and high insertion of the ureter (10.1%). CONCLUSIONS: The underlying etiologies of PUJO in adults remain unclear. This study indicated that obstruction secondary to crossing vessels is the most common cause of obstruction in adults and occurs more frequently than in the pediatric population. Lippincott Williams & Wilkins 2023-06 2022-09-28 /pmc/articles/PMC10489243/ /pubmed/37691990 http://dx.doi.org/10.1097/CU9.0000000000000154 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Reviews
O'Sullivan, Niall J.
Anderson, Steven
Pelviureteric junction obstruction in adults: A systematic review of the literature
title Pelviureteric junction obstruction in adults: A systematic review of the literature
title_full Pelviureteric junction obstruction in adults: A systematic review of the literature
title_fullStr Pelviureteric junction obstruction in adults: A systematic review of the literature
title_full_unstemmed Pelviureteric junction obstruction in adults: A systematic review of the literature
title_short Pelviureteric junction obstruction in adults: A systematic review of the literature
title_sort pelviureteric junction obstruction in adults: a systematic review of the literature
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489243/
https://www.ncbi.nlm.nih.gov/pubmed/37691990
http://dx.doi.org/10.1097/CU9.0000000000000154
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