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Nanobiosensing Based on Electro-Optically Modulated Technology

At the nanoscale, metals exhibit special electrochemical and optical properties, which play an important role in nanobiosensing. In particular, surface plasmon resonance (SPR) based on precious metal nanoparticles, as a kind of tag-free biosensor technology, has brought high sensitivity, high reliab...

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Detalles Bibliográficos
Autores principales: Li, Shuang, Qin, Ziyue, Fu, Jie, Gao, Qiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489767/
https://www.ncbi.nlm.nih.gov/pubmed/37686908
http://dx.doi.org/10.3390/nano13172400
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author Li, Shuang
Qin, Ziyue
Fu, Jie
Gao, Qiya
author_facet Li, Shuang
Qin, Ziyue
Fu, Jie
Gao, Qiya
author_sort Li, Shuang
collection PubMed
description At the nanoscale, metals exhibit special electrochemical and optical properties, which play an important role in nanobiosensing. In particular, surface plasmon resonance (SPR) based on precious metal nanoparticles, as a kind of tag-free biosensor technology, has brought high sensitivity, high reliability, and convenient operation to sensor detection. By applying an electrochemical excitation signal to the nanoplasma device, modulating its surface electron density, and realizing electrochemical coupling SPR, it can effectively complete the joint transmission of electrical and optical signals, increase the resonance shift of the spectrum, and further improve the sensitivity of the designed biosensor. In addition, smartphones are playing an increasingly important role in portable mobile sensor detection systems. These systems typically connect sensing devices to smartphones to perceive different types of information, from optical signals to electrochemical signals, providing ideas for the portability and low-cost design of these sensing systems. Among them, electrochemiluminescence (ECL), as a special electrochemically coupled optical technology, has good application prospects in mobile sensing detection due to its strong anti-interference ability, which is not affected by background light. In this review, the SPR is introduced using nanoparticles, and its response process is analyzed theoretically. Then, the mechanism and sensing application of electrochemistry coupled with SPR and ECL are emphatically introduced. Finally, it extends to the relevant research on electrochemically coupled optical sensing on mobile detection platforms.
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spelling pubmed-104897672023-09-09 Nanobiosensing Based on Electro-Optically Modulated Technology Li, Shuang Qin, Ziyue Fu, Jie Gao, Qiya Nanomaterials (Basel) Review At the nanoscale, metals exhibit special electrochemical and optical properties, which play an important role in nanobiosensing. In particular, surface plasmon resonance (SPR) based on precious metal nanoparticles, as a kind of tag-free biosensor technology, has brought high sensitivity, high reliability, and convenient operation to sensor detection. By applying an electrochemical excitation signal to the nanoplasma device, modulating its surface electron density, and realizing electrochemical coupling SPR, it can effectively complete the joint transmission of electrical and optical signals, increase the resonance shift of the spectrum, and further improve the sensitivity of the designed biosensor. In addition, smartphones are playing an increasingly important role in portable mobile sensor detection systems. These systems typically connect sensing devices to smartphones to perceive different types of information, from optical signals to electrochemical signals, providing ideas for the portability and low-cost design of these sensing systems. Among them, electrochemiluminescence (ECL), as a special electrochemically coupled optical technology, has good application prospects in mobile sensing detection due to its strong anti-interference ability, which is not affected by background light. In this review, the SPR is introduced using nanoparticles, and its response process is analyzed theoretically. Then, the mechanism and sensing application of electrochemistry coupled with SPR and ECL are emphatically introduced. Finally, it extends to the relevant research on electrochemically coupled optical sensing on mobile detection platforms. MDPI 2023-08-23 /pmc/articles/PMC10489767/ /pubmed/37686908 http://dx.doi.org/10.3390/nano13172400 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Li, Shuang
Qin, Ziyue
Fu, Jie
Gao, Qiya
Nanobiosensing Based on Electro-Optically Modulated Technology
title Nanobiosensing Based on Electro-Optically Modulated Technology
title_full Nanobiosensing Based on Electro-Optically Modulated Technology
title_fullStr Nanobiosensing Based on Electro-Optically Modulated Technology
title_full_unstemmed Nanobiosensing Based on Electro-Optically Modulated Technology
title_short Nanobiosensing Based on Electro-Optically Modulated Technology
title_sort nanobiosensing based on electro-optically modulated technology
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10489767/
https://www.ncbi.nlm.nih.gov/pubmed/37686908
http://dx.doi.org/10.3390/nano13172400
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