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The Geriatric Nutritional Risk Index Is an Optimal Evaluation Parameter for Predicting Mortality in Adult All Ages Hemodialysis Patients: A Korean Population-Based Study

The Geriatric Nutritional Risk Index (GNRI) is a nutritional screening tool used for predicting mortality in patients undergoing hemodialysis (HD). This study investigated the cutoff values for the GNRI for predicting mortality in HD patients using Korean HD quality assessment data from 2015. To ide...

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Autores principales: Kim, Do Hyoung, Lee, Young-Ki, Park, Hayne Cho, Kim, Bo Yeon, Lee, Miri, Kim, Gui Ok, Kim, Jinseog, Cho, Ajin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490009/
https://www.ncbi.nlm.nih.gov/pubmed/37686863
http://dx.doi.org/10.3390/nu15173831
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author Kim, Do Hyoung
Lee, Young-Ki
Park, Hayne Cho
Kim, Bo Yeon
Lee, Miri
Kim, Gui Ok
Kim, Jinseog
Cho, Ajin
author_facet Kim, Do Hyoung
Lee, Young-Ki
Park, Hayne Cho
Kim, Bo Yeon
Lee, Miri
Kim, Gui Ok
Kim, Jinseog
Cho, Ajin
author_sort Kim, Do Hyoung
collection PubMed
description The Geriatric Nutritional Risk Index (GNRI) is a nutritional screening tool used for predicting mortality in patients undergoing hemodialysis (HD). This study investigated the cutoff values for the GNRI for predicting mortality in HD patients using Korean HD quality assessment data from 2015. To identify the optimal GNRI cutoff value, we used Harrell’s C-index with multivariate Cox regression models. The highest value of C-index was identified as the cutoff value of GNRI for all-cause mortality in this population. In total, 34,933 patients were included; 90.8 of GNRI was the highest value of C-index, and it was used as a cutoff value to predict mortality; 3311 patients (9.5%) had GNRI values < 90.8, and there were 12,499 deaths during the study period. The mean follow-up period was 53.7 months. The crude mortality rates in patients with GNRI values < 90.8 and ≥ 90.8 were 160.4/1000 and 73.2/1000 person-years respectively. In the fully adjusted Cox model, patients with a GNRI < 90.8 had a 1.78 times higher risk of mortality than those with a GNRI ≥ 90.8. These findings suggest that the optimal GNRI cutoff value is 90.8 for predicting mortality in maintenance HD patients.
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spelling pubmed-104900092023-09-09 The Geriatric Nutritional Risk Index Is an Optimal Evaluation Parameter for Predicting Mortality in Adult All Ages Hemodialysis Patients: A Korean Population-Based Study Kim, Do Hyoung Lee, Young-Ki Park, Hayne Cho Kim, Bo Yeon Lee, Miri Kim, Gui Ok Kim, Jinseog Cho, Ajin Nutrients Article The Geriatric Nutritional Risk Index (GNRI) is a nutritional screening tool used for predicting mortality in patients undergoing hemodialysis (HD). This study investigated the cutoff values for the GNRI for predicting mortality in HD patients using Korean HD quality assessment data from 2015. To identify the optimal GNRI cutoff value, we used Harrell’s C-index with multivariate Cox regression models. The highest value of C-index was identified as the cutoff value of GNRI for all-cause mortality in this population. In total, 34,933 patients were included; 90.8 of GNRI was the highest value of C-index, and it was used as a cutoff value to predict mortality; 3311 patients (9.5%) had GNRI values < 90.8, and there were 12,499 deaths during the study period. The mean follow-up period was 53.7 months. The crude mortality rates in patients with GNRI values < 90.8 and ≥ 90.8 were 160.4/1000 and 73.2/1000 person-years respectively. In the fully adjusted Cox model, patients with a GNRI < 90.8 had a 1.78 times higher risk of mortality than those with a GNRI ≥ 90.8. These findings suggest that the optimal GNRI cutoff value is 90.8 for predicting mortality in maintenance HD patients. MDPI 2023-09-01 /pmc/articles/PMC10490009/ /pubmed/37686863 http://dx.doi.org/10.3390/nu15173831 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kim, Do Hyoung
Lee, Young-Ki
Park, Hayne Cho
Kim, Bo Yeon
Lee, Miri
Kim, Gui Ok
Kim, Jinseog
Cho, Ajin
The Geriatric Nutritional Risk Index Is an Optimal Evaluation Parameter for Predicting Mortality in Adult All Ages Hemodialysis Patients: A Korean Population-Based Study
title The Geriatric Nutritional Risk Index Is an Optimal Evaluation Parameter for Predicting Mortality in Adult All Ages Hemodialysis Patients: A Korean Population-Based Study
title_full The Geriatric Nutritional Risk Index Is an Optimal Evaluation Parameter for Predicting Mortality in Adult All Ages Hemodialysis Patients: A Korean Population-Based Study
title_fullStr The Geriatric Nutritional Risk Index Is an Optimal Evaluation Parameter for Predicting Mortality in Adult All Ages Hemodialysis Patients: A Korean Population-Based Study
title_full_unstemmed The Geriatric Nutritional Risk Index Is an Optimal Evaluation Parameter for Predicting Mortality in Adult All Ages Hemodialysis Patients: A Korean Population-Based Study
title_short The Geriatric Nutritional Risk Index Is an Optimal Evaluation Parameter for Predicting Mortality in Adult All Ages Hemodialysis Patients: A Korean Population-Based Study
title_sort geriatric nutritional risk index is an optimal evaluation parameter for predicting mortality in adult all ages hemodialysis patients: a korean population-based study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490009/
https://www.ncbi.nlm.nih.gov/pubmed/37686863
http://dx.doi.org/10.3390/nu15173831
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