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Feeding High-Fat Diet Accelerates Development of Peripheral and Central Insulin Resistance and Inflammation and Worsens AD-like Pathology in APP/PS1 Mice
Alzheimer’s disease (AD) is a progressive brain disorder characterized by extracellular amyloid-β (Aβ) plaques, intracellular neurofibrillary tangles formed by hyperphosphorylated Tau protein and neuroinflammation. Previous research has shown that obesity and type 2 diabetes mellitus, underlined by...
Autores principales: | Mengr, Anna, Strnadová, Veronika, Strnad, Štěpán, Vrkoslav, Vladimír, Pelantová, Helena, Kuzma, Marek, Comptdaer, Thomas, Železná, Blanka, Kuneš, Jaroslav, Galas, Marie-Christine, Pačesová, Andrea, Maletínská, Lenka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490051/ https://www.ncbi.nlm.nih.gov/pubmed/37686722 http://dx.doi.org/10.3390/nu15173690 |
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