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Synthesis of Spirocyclopropane-Containing 4H-Pyrazolo[1,5-a]indoles via Alkylative Dearomatization and Intramolecular N-Imination of an Indole–O-(Methylsulfonyl)oxime

In this paper, we report the synthesis of spirocyclopropane-containing 4H-pyrazolo[1,5-a]indoles 6a–e via alkylative dearomatization and intramolecular N-imination of indole–O-(methylsulfonyl)oxime 11. Starting materials tryptophol (7) and 2-bromocyclopetanone (8) were reacted in the presence of HBF...

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Detalles Bibliográficos
Autores principales:	Huang, Jiann-Jyh, Liao, Hung-Chun, Hsu, Cheng-En, Liu, Yan-Ru, Chang, Yi-Fu, Chou, Shan-Yen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490174/ https://www.ncbi.nlm.nih.gov/pubmed/37687203 http://dx.doi.org/10.3390/molecules28176374

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