Cargando…

Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract

Several species from the genus Tragia L. in the family Euphorbiaceae are part of the ethnomedicine of traditional cultures, and have a variety of uses. Tragia volubilis L. is a species spread through tropical America and Africa with several ethnomedical uses, particularly for wound healing and repro...

Descripción completa

Detalles Bibliográficos
Autores principales: Romero-Benavides, Juan Carlos, Atiencie-Valarezo, Nora Cecilia, Duarte-Casar, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490261/
https://www.ncbi.nlm.nih.gov/pubmed/37687385
http://dx.doi.org/10.3390/plants12173139
_version_ 1785103803237793792
author Romero-Benavides, Juan Carlos
Atiencie-Valarezo, Nora Cecilia
Duarte-Casar, Rodrigo
author_facet Romero-Benavides, Juan Carlos
Atiencie-Valarezo, Nora Cecilia
Duarte-Casar, Rodrigo
author_sort Romero-Benavides, Juan Carlos
collection PubMed
description Several species from the genus Tragia L. in the family Euphorbiaceae are part of the ethnomedicine of traditional cultures, and have a variety of uses. Tragia volubilis L. is a species spread through tropical America and Africa with several ethnomedical uses, particularly for wound healing and reproductive issues. In this study, we assess the phytochemical composition and antioxidant activity of the methanolic extract of the aerial parts of T. volubilis collected in southern Ecuador. The phytochemical screening of the extract shows the preliminary presence of carbohydrates, alkaloids, flavonoids, and tannins. The extract shows an Antioxidant Activity Index of 1.14, interpreted as strong antioxidant activity. Four flavonoid compounds were isolated through chromatographic procedures and identified through NMR spectroscopy: avicularin, quercitrin, afzelin, and amentoflavone. The biological activity of these compounds matches the ethnopharmacological uses of the species. This is the first phytochemical study of T. volubilis and supports its traditional medicinal uses.
format Online
Article
Text
id pubmed-10490261
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104902612023-09-09 Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract Romero-Benavides, Juan Carlos Atiencie-Valarezo, Nora Cecilia Duarte-Casar, Rodrigo Plants (Basel) Brief Report Several species from the genus Tragia L. in the family Euphorbiaceae are part of the ethnomedicine of traditional cultures, and have a variety of uses. Tragia volubilis L. is a species spread through tropical America and Africa with several ethnomedical uses, particularly for wound healing and reproductive issues. In this study, we assess the phytochemical composition and antioxidant activity of the methanolic extract of the aerial parts of T. volubilis collected in southern Ecuador. The phytochemical screening of the extract shows the preliminary presence of carbohydrates, alkaloids, flavonoids, and tannins. The extract shows an Antioxidant Activity Index of 1.14, interpreted as strong antioxidant activity. Four flavonoid compounds were isolated through chromatographic procedures and identified through NMR spectroscopy: avicularin, quercitrin, afzelin, and amentoflavone. The biological activity of these compounds matches the ethnopharmacological uses of the species. This is the first phytochemical study of T. volubilis and supports its traditional medicinal uses. MDPI 2023-08-31 /pmc/articles/PMC10490261/ /pubmed/37687385 http://dx.doi.org/10.3390/plants12173139 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Romero-Benavides, Juan Carlos
Atiencie-Valarezo, Nora Cecilia
Duarte-Casar, Rodrigo
Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract
title Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract
title_full Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract
title_fullStr Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract
title_full_unstemmed Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract
title_short Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract
title_sort flavonoid composition and antioxidant activity of tragia volubilis l. methanolic extract
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490261/
https://www.ncbi.nlm.nih.gov/pubmed/37687385
http://dx.doi.org/10.3390/plants12173139
work_keys_str_mv AT romerobenavidesjuancarlos flavonoidcompositionandantioxidantactivityoftragiavolubilislmethanolicextract
AT atiencievalarezonoracecilia flavonoidcompositionandantioxidantactivityoftragiavolubilislmethanolicextract
AT duartecasarrodrigo flavonoidcompositionandantioxidantactivityoftragiavolubilislmethanolicextract