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In Silico Modeling and Structural Analysis of Soluble Epoxide Hydrolase Inhibitors for Enhanced Therapeutic Design

Human soluble epoxide hydrolase (sEH), a dual-functioning homodimeric enzyme with hydrolase and phosphatase activities, is known for its pivotal role in the hydrolysis of epoxyeicosatrienoic acids. Inhibitors targeting sEH have shown promising potential in the treatment of various life-threatening d...

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Detalles Bibliográficos
Autores principales: Sar, Shuvam, Mitra, Soumya, Panda, Parthasarathi, Mandal, Subhash C., Ghosh, Nilanjan, Halder, Amit Kumar, Cordeiro, Maria Natalia D. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490281/
https://www.ncbi.nlm.nih.gov/pubmed/37687207
http://dx.doi.org/10.3390/molecules28176379

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