Cargando…

Triple Reporter Assay: A Non-Overlapping Luciferase Assay for the Measurement of Complex Macromolecular Regulation in Cancer Cells Using a New Mushroom Luciferase–Luciferin Pair

This study demonstrates the development of a humanized luciferase imaging reporter based on a recently discovered mushroom luciferase (Luz) from Neonothopanus nambi. In vitro and in vivo assessments showed that human-codon-optimized Luz (hLuz) has significantly higher activity than native Luz in var...

Descripción completa

Detalles Bibliográficos
Autores principales: Mujawar, Aaiyas, Phadte, Pratham, Palkina, Ksenia A., Markina, Nadezhda M., Mohammad, Ameena, Thakur, Bhushan L., Sarkisyan, Karen S., Balakireva, Anastasia V., Ray, Pritha, Yamplosky, Ilia, De, Abhijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490530/
https://www.ncbi.nlm.nih.gov/pubmed/37687774
http://dx.doi.org/10.3390/s23177313