Cargando…

The Stress Phase Angle Measurement Using Spectral Domain Optical Coherence Tomography

The stress phase angle (SPA), defined as the temporal phase angle between circumferential stress (CS) in the arterial wall and wall shear stress (WSS), is utilized to investigate the interactions between CS and WSS. SPA serves as an important parameter for the early diagnosis of cardiovascular disea...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yuqian, Zhu, Zhibo, Jiang, Huiwen, Yu, Yao, Liu, Jian, Luan, Jingmin, Wang, Yi, Ma, Zhenhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490597/
https://www.ncbi.nlm.nih.gov/pubmed/37688052
http://dx.doi.org/10.3390/s23177597
_version_ 1785103876630773760
author Zhao, Yuqian
Zhu, Zhibo
Jiang, Huiwen
Yu, Yao
Liu, Jian
Luan, Jingmin
Wang, Yi
Ma, Zhenhe
author_facet Zhao, Yuqian
Zhu, Zhibo
Jiang, Huiwen
Yu, Yao
Liu, Jian
Luan, Jingmin
Wang, Yi
Ma, Zhenhe
author_sort Zhao, Yuqian
collection PubMed
description The stress phase angle (SPA), defined as the temporal phase angle between circumferential stress (CS) in the arterial wall and wall shear stress (WSS), is utilized to investigate the interactions between CS and WSS. SPA serves as an important parameter for the early diagnosis of cardiovascular disease. In this study, we proposed a novel method for measuring SPA using spectral domain optical coherence tomography (SD-OCT). The multi-M-mode scan strategy is adopted for interference spectrum acquisition. The phases of CS and WSS are extracted from the corresponding structural and flow velocity images of SD-OCT. The method is validated by measuring SPA in the outflow tract (OFT) of chick embryonic hearts and the common carotid artery of mice. To the best of our knowledge, this is the first time that OCT has been used for SPA measurement.
format Online
Article
Text
id pubmed-10490597
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104905972023-09-09 The Stress Phase Angle Measurement Using Spectral Domain Optical Coherence Tomography Zhao, Yuqian Zhu, Zhibo Jiang, Huiwen Yu, Yao Liu, Jian Luan, Jingmin Wang, Yi Ma, Zhenhe Sensors (Basel) Article The stress phase angle (SPA), defined as the temporal phase angle between circumferential stress (CS) in the arterial wall and wall shear stress (WSS), is utilized to investigate the interactions between CS and WSS. SPA serves as an important parameter for the early diagnosis of cardiovascular disease. In this study, we proposed a novel method for measuring SPA using spectral domain optical coherence tomography (SD-OCT). The multi-M-mode scan strategy is adopted for interference spectrum acquisition. The phases of CS and WSS are extracted from the corresponding structural and flow velocity images of SD-OCT. The method is validated by measuring SPA in the outflow tract (OFT) of chick embryonic hearts and the common carotid artery of mice. To the best of our knowledge, this is the first time that OCT has been used for SPA measurement. MDPI 2023-09-01 /pmc/articles/PMC10490597/ /pubmed/37688052 http://dx.doi.org/10.3390/s23177597 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhao, Yuqian
Zhu, Zhibo
Jiang, Huiwen
Yu, Yao
Liu, Jian
Luan, Jingmin
Wang, Yi
Ma, Zhenhe
The Stress Phase Angle Measurement Using Spectral Domain Optical Coherence Tomography
title The Stress Phase Angle Measurement Using Spectral Domain Optical Coherence Tomography
title_full The Stress Phase Angle Measurement Using Spectral Domain Optical Coherence Tomography
title_fullStr The Stress Phase Angle Measurement Using Spectral Domain Optical Coherence Tomography
title_full_unstemmed The Stress Phase Angle Measurement Using Spectral Domain Optical Coherence Tomography
title_short The Stress Phase Angle Measurement Using Spectral Domain Optical Coherence Tomography
title_sort stress phase angle measurement using spectral domain optical coherence tomography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490597/
https://www.ncbi.nlm.nih.gov/pubmed/37688052
http://dx.doi.org/10.3390/s23177597
work_keys_str_mv AT zhaoyuqian thestressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT zhuzhibo thestressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT jianghuiwen thestressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT yuyao thestressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT liujian thestressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT luanjingmin thestressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT wangyi thestressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT mazhenhe thestressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT zhaoyuqian stressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT zhuzhibo stressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT jianghuiwen stressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT yuyao stressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT liujian stressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT luanjingmin stressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT wangyi stressphaseanglemeasurementusingspectraldomainopticalcoherencetomography
AT mazhenhe stressphaseanglemeasurementusingspectraldomainopticalcoherencetomography