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Numerical Investigation on High-Performance Cu-Based Surface Plasmon Resonance Sensor for Biosensing Application

This numerical research presents a simple hybrid structure comprised of TiO(2)-Cu-BaTiO(3) for a modified Kretschmann configuration that exhibits high sensitivity and high resolution for biosensing applications through an angular interrogation method. Recently, copper (Cu) emerged as an exceptional...

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Autores principales: Muthumanikkam, M., Vibisha, Alagu, Lordwin Prabhakar, Michael Cecil, Suresh, Ponnan, Rajesh, Karupiya Balasundaram, Jaroszewicz, Zbigniew, Jha, Rajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490717/
https://www.ncbi.nlm.nih.gov/pubmed/37687950
http://dx.doi.org/10.3390/s23177495
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author Muthumanikkam, M.
Vibisha, Alagu
Lordwin Prabhakar, Michael Cecil
Suresh, Ponnan
Rajesh, Karupiya Balasundaram
Jaroszewicz, Zbigniew
Jha, Rajan
author_facet Muthumanikkam, M.
Vibisha, Alagu
Lordwin Prabhakar, Michael Cecil
Suresh, Ponnan
Rajesh, Karupiya Balasundaram
Jaroszewicz, Zbigniew
Jha, Rajan
author_sort Muthumanikkam, M.
collection PubMed
description This numerical research presents a simple hybrid structure comprised of TiO(2)-Cu-BaTiO(3) for a modified Kretschmann configuration that exhibits high sensitivity and high resolution for biosensing applications through an angular interrogation method. Recently, copper (Cu) emerged as an exceptional choice as a plasmonic metal for developing surface plasmon sensors (SPR) with high resolution as it yields finer, thinner SPR curves than Ag and Au. As copper is prone to oxidation, especially in ambient conditions, the proposed structure involves the utilization of barium titanate (BaTiO(3)) film as a protection layer that not only preserves Cu film from oxidizing but enhances the performance of the sensor to a great extent. Numerical results also show that the utilization of a thin adhesive layer of titanium dioxide (TiO(2)) between the prism base and Cu film not only induces strong interaction between them but also enhances the performance of the sensor. Such a configuration, upon suitable optimization of the thickness of each layer, is found to enhance sensitivity as high as 552°/RIU with a figure of merit (FOM) of 136.97 RIU(−1). This suggested biosensor design with enhanced sensitivity is expected to enable long-term detection with greater accuracy and sensitivity even when using Cu as a plasmonic metal.
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spelling pubmed-104907172023-09-09 Numerical Investigation on High-Performance Cu-Based Surface Plasmon Resonance Sensor for Biosensing Application Muthumanikkam, M. Vibisha, Alagu Lordwin Prabhakar, Michael Cecil Suresh, Ponnan Rajesh, Karupiya Balasundaram Jaroszewicz, Zbigniew Jha, Rajan Sensors (Basel) Article This numerical research presents a simple hybrid structure comprised of TiO(2)-Cu-BaTiO(3) for a modified Kretschmann configuration that exhibits high sensitivity and high resolution for biosensing applications through an angular interrogation method. Recently, copper (Cu) emerged as an exceptional choice as a plasmonic metal for developing surface plasmon sensors (SPR) with high resolution as it yields finer, thinner SPR curves than Ag and Au. As copper is prone to oxidation, especially in ambient conditions, the proposed structure involves the utilization of barium titanate (BaTiO(3)) film as a protection layer that not only preserves Cu film from oxidizing but enhances the performance of the sensor to a great extent. Numerical results also show that the utilization of a thin adhesive layer of titanium dioxide (TiO(2)) between the prism base and Cu film not only induces strong interaction between them but also enhances the performance of the sensor. Such a configuration, upon suitable optimization of the thickness of each layer, is found to enhance sensitivity as high as 552°/RIU with a figure of merit (FOM) of 136.97 RIU(−1). This suggested biosensor design with enhanced sensitivity is expected to enable long-term detection with greater accuracy and sensitivity even when using Cu as a plasmonic metal. MDPI 2023-08-29 /pmc/articles/PMC10490717/ /pubmed/37687950 http://dx.doi.org/10.3390/s23177495 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Muthumanikkam, M.
Vibisha, Alagu
Lordwin Prabhakar, Michael Cecil
Suresh, Ponnan
Rajesh, Karupiya Balasundaram
Jaroszewicz, Zbigniew
Jha, Rajan
Numerical Investigation on High-Performance Cu-Based Surface Plasmon Resonance Sensor for Biosensing Application
title Numerical Investigation on High-Performance Cu-Based Surface Plasmon Resonance Sensor for Biosensing Application
title_full Numerical Investigation on High-Performance Cu-Based Surface Plasmon Resonance Sensor for Biosensing Application
title_fullStr Numerical Investigation on High-Performance Cu-Based Surface Plasmon Resonance Sensor for Biosensing Application
title_full_unstemmed Numerical Investigation on High-Performance Cu-Based Surface Plasmon Resonance Sensor for Biosensing Application
title_short Numerical Investigation on High-Performance Cu-Based Surface Plasmon Resonance Sensor for Biosensing Application
title_sort numerical investigation on high-performance cu-based surface plasmon resonance sensor for biosensing application
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490717/
https://www.ncbi.nlm.nih.gov/pubmed/37687950
http://dx.doi.org/10.3390/s23177495
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