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In silico and in vitro potentials of crocin and amphotericin B on Leishmania major: Multiple synergistic mechanisms of actions
A significant barrier to optimal antileishmanial treatment is low efficacy and the emergence of drug resistance. Multiple approaches were used to monitor and assess crocin (a central component of saffron) mixed with amphotericin B (AmpB) potential in silico and in vitro consequences. The binding beh...
Autores principales: | Salarkia, Ehsan, Sharifi, Iraj, Keyhani, Alireza, Tavakoli Oliaee, Razieh, Khosravi, Ahmad, Sharifi, Fatemeh, Bamorovat, Mehdi, Babaei, Zahra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490900/ https://www.ncbi.nlm.nih.gov/pubmed/37682934 http://dx.doi.org/10.1371/journal.pone.0291322 |
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