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In silico and in vitro potentials of crocin and amphotericin B on Leishmania major: Multiple synergistic mechanisms of actions

A significant barrier to optimal antileishmanial treatment is low efficacy and the emergence of drug resistance. Multiple approaches were used to monitor and assess crocin (a central component of saffron) mixed with amphotericin B (AmpB) potential in silico and in vitro consequences. The binding beh...

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Detalles Bibliográficos
Autores principales: Salarkia, Ehsan, Sharifi, Iraj, Keyhani, Alireza, Tavakoli Oliaee, Razieh, Khosravi, Ahmad, Sharifi, Fatemeh, Bamorovat, Mehdi, Babaei, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490900/
https://www.ncbi.nlm.nih.gov/pubmed/37682934
http://dx.doi.org/10.1371/journal.pone.0291322

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