Clinical protocol: Feasibility of evaluating abemaciclib neuropharmacokinetics of diffuse midline glioma using intratumoral microdialysis

Diffuse midline gliomas (DMG) are the most aggressive brain tumors of childhood and young adults, with documented 2-year survival rates <10%. Treatment failure is due in part to the function of the BBB. Intratumoral microdialysis sampling is an effective tool to determine brain entry of varied ag...

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Detalles Bibliográficos
Autores principales: Nduom, Edjah K., Glod, John, Brown, Desmond A., Fagan, Margaret, Dalmage, Mahalia, Heiss, John, Steinberg, Seth M., Peer, Cody, Figg, William D., Jackson, Sadhana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490936/
https://www.ncbi.nlm.nih.gov/pubmed/37682953
http://dx.doi.org/10.1371/journal.pone.0291068

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