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Triptans utilization in Italian population: A real-life study in community pharmacies

The term Headache Disorders (HD) refers to a number of nervous system pathologies characterised by recurrent headaches. Despite the serious impact HD have on the health system, society, and the economy, these are an underestimated, underdiagnosed, and, hence, undertreated phenomenon. Triptans are th...

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Autores principales: Baratta, Francesca, Allais, Gianni, Gnavi, Roberto, Scarinzi, Cecilia, Enri, Lorenzo Ravetto, Rolando, Sara, Spadea, Teresa, Costa, Giuseppe, Benedetto, Chiara, Mana, Massimo, Giaccone, Mario, Mandelli, Andrea, Manzoni, Gian Camillo, Bussone, Gennaro, Brusa, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490971/
https://www.ncbi.nlm.nih.gov/pubmed/37682959
http://dx.doi.org/10.1371/journal.pone.0291323
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author Baratta, Francesca
Allais, Gianni
Gnavi, Roberto
Scarinzi, Cecilia
Enri, Lorenzo Ravetto
Rolando, Sara
Spadea, Teresa
Costa, Giuseppe
Benedetto, Chiara
Mana, Massimo
Giaccone, Mario
Mandelli, Andrea
Manzoni, Gian Camillo
Bussone, Gennaro
Brusa, Paola
author_facet Baratta, Francesca
Allais, Gianni
Gnavi, Roberto
Scarinzi, Cecilia
Enri, Lorenzo Ravetto
Rolando, Sara
Spadea, Teresa
Costa, Giuseppe
Benedetto, Chiara
Mana, Massimo
Giaccone, Mario
Mandelli, Andrea
Manzoni, Gian Camillo
Bussone, Gennaro
Brusa, Paola
author_sort Baratta, Francesca
collection PubMed
description The term Headache Disorders (HD) refers to a number of nervous system pathologies characterised by recurrent headaches. Despite the serious impact HD have on the health system, society, and the economy, these are an underestimated, underdiagnosed, and, hence, undertreated phenomenon. Triptans are the first-line therapy for the acute treatment of moderate to severe migraine but their utilization is still inadequate, perhaps also because in Italy no triptan can be bought without a medical prescription. In this article, the data from a 2016–2017 study has been further analysed with the aim of evaluating any associations between the use of triptans and the other series of variables identified in the questionnaire. This further analysis has been connected to the role that community pharmacies could play on this issue. The questionnaire was administered to 4,424 pharmacy users by 610 purposely trained pharmacists working in 514 pharmacies. The survey was carried out in 19 of the 20 Italian regions. The data shows that only 25% of patients suffering from HDs are prescribed triptans. Older patients, those with definite migraines, and those with a chronic disorder resort more frequently to this class of pharmaceuticals, as do those patients in care at a specialist headache centre. The multivariable analysis also confirmed these results. Our study, which performed a direct detection, in real life, on patients requesting pharmacological treatment for a migraine headache, therefore confirmed the need to investigate the reasons behind the low use and prescription of triptans in the Italian population. Moreover, any future studies should take advantage of community pharmacies, plan actions that would allow a series of evaluations over time of the requirements of migraineurs, and establish a process to put these patients under the care of the pharmacy to ensure adherence to therapy.
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spelling pubmed-104909712023-09-09 Triptans utilization in Italian population: A real-life study in community pharmacies Baratta, Francesca Allais, Gianni Gnavi, Roberto Scarinzi, Cecilia Enri, Lorenzo Ravetto Rolando, Sara Spadea, Teresa Costa, Giuseppe Benedetto, Chiara Mana, Massimo Giaccone, Mario Mandelli, Andrea Manzoni, Gian Camillo Bussone, Gennaro Brusa, Paola PLoS One Research Article The term Headache Disorders (HD) refers to a number of nervous system pathologies characterised by recurrent headaches. Despite the serious impact HD have on the health system, society, and the economy, these are an underestimated, underdiagnosed, and, hence, undertreated phenomenon. Triptans are the first-line therapy for the acute treatment of moderate to severe migraine but their utilization is still inadequate, perhaps also because in Italy no triptan can be bought without a medical prescription. In this article, the data from a 2016–2017 study has been further analysed with the aim of evaluating any associations between the use of triptans and the other series of variables identified in the questionnaire. This further analysis has been connected to the role that community pharmacies could play on this issue. The questionnaire was administered to 4,424 pharmacy users by 610 purposely trained pharmacists working in 514 pharmacies. The survey was carried out in 19 of the 20 Italian regions. The data shows that only 25% of patients suffering from HDs are prescribed triptans. Older patients, those with definite migraines, and those with a chronic disorder resort more frequently to this class of pharmaceuticals, as do those patients in care at a specialist headache centre. The multivariable analysis also confirmed these results. Our study, which performed a direct detection, in real life, on patients requesting pharmacological treatment for a migraine headache, therefore confirmed the need to investigate the reasons behind the low use and prescription of triptans in the Italian population. Moreover, any future studies should take advantage of community pharmacies, plan actions that would allow a series of evaluations over time of the requirements of migraineurs, and establish a process to put these patients under the care of the pharmacy to ensure adherence to therapy. Public Library of Science 2023-09-08 /pmc/articles/PMC10490971/ /pubmed/37682959 http://dx.doi.org/10.1371/journal.pone.0291323 Text en © 2023 Baratta et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Baratta, Francesca
Allais, Gianni
Gnavi, Roberto
Scarinzi, Cecilia
Enri, Lorenzo Ravetto
Rolando, Sara
Spadea, Teresa
Costa, Giuseppe
Benedetto, Chiara
Mana, Massimo
Giaccone, Mario
Mandelli, Andrea
Manzoni, Gian Camillo
Bussone, Gennaro
Brusa, Paola
Triptans utilization in Italian population: A real-life study in community pharmacies
title Triptans utilization in Italian population: A real-life study in community pharmacies
title_full Triptans utilization in Italian population: A real-life study in community pharmacies
title_fullStr Triptans utilization in Italian population: A real-life study in community pharmacies
title_full_unstemmed Triptans utilization in Italian population: A real-life study in community pharmacies
title_short Triptans utilization in Italian population: A real-life study in community pharmacies
title_sort triptans utilization in italian population: a real-life study in community pharmacies
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10490971/
https://www.ncbi.nlm.nih.gov/pubmed/37682959
http://dx.doi.org/10.1371/journal.pone.0291323
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