HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide

Elicitation of antibodies that neutralize the tier-2 neutralization-resistant isolates that typify HIV-1 transmission has been a long-sought goal. Success with prefusion-stabilized envelope trimers eliciting autologous neutralizing antibodies has been reported in multiple vaccine-test species, thoug...

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Detalles Bibliográficos
Autores principales: Wang, Shuishu, Matassoli, Flavio, Zhang, Baoshan, Liu, Tracy, Shen, Chen-Hsiang, Bylund, Tatsiana, Johnston, Timothy, Henry, Amy R., Teng, I-Ting, Tripathi, Prabhanshu, Becker, Jordan E., Changela, Anita, Chaudhary, Ridhi, Cheng, Cheng, Gaudinski, Martin, Gorman, Jason, Harris, Darcy R., Lee, Myungjin, Morano, Nicholas C., Novik, Laura, O’Dell, Sijy, Olia, Adam S., Parchment, Danealle K., Rawi, Reda, Roberts-Torres, Jesmine, Stephens, Tyler, Tsybovsky, Yaroslav, Wang, Danyi, Van Wazer, David J., Zhou, Tongqing, Doria-Rose, Nicole A., Koup, Richard A., Shapiro, Lawrence, Douek, Daniel C., McDermott, Adrian B., Kwong, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491024/
https://www.ncbi.nlm.nih.gov/pubmed/37436899
http://dx.doi.org/10.1016/j.celrep.2023.112755

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