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Case series of central retinal artery occlusion in COVID-19-associated rhino-orbital-cerebral mucormycosis

Rhino orbital Mucormycosis caused by filamentous fungus of mucoraceae family was considered a rare disease affecting immunocompromised and diabetics with ketoacidosis until the recent COVID 19 pandemic. We are presenting a series of six cases of Rhino orbital cerebral Mucormycosis with central retin...

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Autores principales: Kamath, Gurudutt M, Jeganathan, Sangeetha, Salim, Sreelakshmi, Antony, Reeja Mariam, Kamath, Ajay R, Hiran, Harshitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491029/
https://www.ncbi.nlm.nih.gov/pubmed/37417144
http://dx.doi.org/10.4103/IJO.IJO_3123_22
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author Kamath, Gurudutt M
Jeganathan, Sangeetha
Salim, Sreelakshmi
Antony, Reeja Mariam
Kamath, Ajay R
Hiran, Harshitha
author_facet Kamath, Gurudutt M
Jeganathan, Sangeetha
Salim, Sreelakshmi
Antony, Reeja Mariam
Kamath, Ajay R
Hiran, Harshitha
author_sort Kamath, Gurudutt M
collection PubMed
description Rhino orbital Mucormycosis caused by filamentous fungus of mucoraceae family was considered a rare disease affecting immunocompromised and diabetics with ketoacidosis until the recent COVID 19 pandemic. We are presenting a series of six cases of Rhino orbital cerebral Mucormycosis with central retinal artery occlusion. All six cases had common history of COVID 19 infection in recent past with sinusitis, proptosis and total ophthalmoplegia with central retinal artery occlusion on presentation. MR imaging showed invasive pan sinusitis with orbital and cerebral involvement. Urgent debridement was done and histopathological examination showed broad, filamentous aseptate fungi suggestive of Mucormycosis. All patients inspite of intravenous Amphotericin B with local debridement did not show any improvement and expired within a week of presentation. Hence our study shows poor prognosis of post covid 19 associated Mucormycosis with central retinal artery occlusion.
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spelling pubmed-104910292023-09-09 Case series of central retinal artery occlusion in COVID-19-associated rhino-orbital-cerebral mucormycosis Kamath, Gurudutt M Jeganathan, Sangeetha Salim, Sreelakshmi Antony, Reeja Mariam Kamath, Ajay R Hiran, Harshitha Indian J Ophthalmol Case Reports Rhino orbital Mucormycosis caused by filamentous fungus of mucoraceae family was considered a rare disease affecting immunocompromised and diabetics with ketoacidosis until the recent COVID 19 pandemic. We are presenting a series of six cases of Rhino orbital cerebral Mucormycosis with central retinal artery occlusion. All six cases had common history of COVID 19 infection in recent past with sinusitis, proptosis and total ophthalmoplegia with central retinal artery occlusion on presentation. MR imaging showed invasive pan sinusitis with orbital and cerebral involvement. Urgent debridement was done and histopathological examination showed broad, filamentous aseptate fungi suggestive of Mucormycosis. All patients inspite of intravenous Amphotericin B with local debridement did not show any improvement and expired within a week of presentation. Hence our study shows poor prognosis of post covid 19 associated Mucormycosis with central retinal artery occlusion. Wolters Kluwer - Medknow 2023-07 2023-07-05 /pmc/articles/PMC10491029/ /pubmed/37417144 http://dx.doi.org/10.4103/IJO.IJO_3123_22 Text en Copyright: © 2023 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Kamath, Gurudutt M
Jeganathan, Sangeetha
Salim, Sreelakshmi
Antony, Reeja Mariam
Kamath, Ajay R
Hiran, Harshitha
Case series of central retinal artery occlusion in COVID-19-associated rhino-orbital-cerebral mucormycosis
title Case series of central retinal artery occlusion in COVID-19-associated rhino-orbital-cerebral mucormycosis
title_full Case series of central retinal artery occlusion in COVID-19-associated rhino-orbital-cerebral mucormycosis
title_fullStr Case series of central retinal artery occlusion in COVID-19-associated rhino-orbital-cerebral mucormycosis
title_full_unstemmed Case series of central retinal artery occlusion in COVID-19-associated rhino-orbital-cerebral mucormycosis
title_short Case series of central retinal artery occlusion in COVID-19-associated rhino-orbital-cerebral mucormycosis
title_sort case series of central retinal artery occlusion in covid-19-associated rhino-orbital-cerebral mucormycosis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491029/
https://www.ncbi.nlm.nih.gov/pubmed/37417144
http://dx.doi.org/10.4103/IJO.IJO_3123_22
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