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Orthogonal targeting of SAC1 to mitochondria implicates ORP2 as a major player in PM PI4P turnover

Oxysterol binding protein (OSBP)-related proteins (ORPs) 5 and 8 have been shown to deplete the lipid phosphatidylinositol 4-phosphate (PI4P) at sites of membrane contact between the endoplasmic reticulum (ER) and plasma membrane (PM). This is believed to be caused by transport of PI4P from the PM t...

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Detalles Bibliográficos
Autores principales:	Doyle, Colleen P., Rectenwald, Andrew, Timple, Liz, Hammond, Gerald R. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491111/ https://www.ncbi.nlm.nih.gov/pubmed/37693626 http://dx.doi.org/10.1101/2023.08.28.555163

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