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Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins

High levels of HDL-C are correlated with a decreased risk of cardiovascular disease. HDL-C levels are modulated in part by the secreted phospholipase, endothelial lipase (EL), which hydrolyzes the phospholipids of HDL and decreases circulating HDL-C concentrations. A 584C/T polymorphism in LIPG, the...

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Detalles Bibliográficos
Autores principales: Sylvers-Davie, Kelli L., Bierstedt, Kaleb C., Schnieders, Michael J., Davies, Brandon S. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491130/
https://www.ncbi.nlm.nih.gov/pubmed/37693454
http://dx.doi.org/10.1101/2023.08.18.553740