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NRF2 Dysregulation in Mice Leads to Inadequate Beta-Cell Mass Expansion during Pregnancy and Gestational Diabetes

The late stages of the mammalian pregnancy are accompanied with increased insulin resistance due to the increased glucose demand of the growing fetus. Therefore, as a compensatory response to maintain the maternal normal blood glucose levels, maternal beta-cell mass expands leading to increased insu...

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Detalles Bibliográficos
Autores principales: Baumel-Alterzon, Sharon, Tse, Isabelle, Heidery, Fatema, Garcia-Ocaña, Adolfo, Scott, Donald K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491153/
https://www.ncbi.nlm.nih.gov/pubmed/37693560
http://dx.doi.org/10.1101/2023.08.28.555207