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NRF2 Dysregulation in Mice Leads to Inadequate Beta-Cell Mass Expansion during Pregnancy and Gestational Diabetes
The late stages of the mammalian pregnancy are accompanied with increased insulin resistance due to the increased glucose demand of the growing fetus. Therefore, as a compensatory response to maintain the maternal normal blood glucose levels, maternal beta-cell mass expands leading to increased insu...
Autores principales: | Baumel-Alterzon, Sharon, Tse, Isabelle, Heidery, Fatema, Garcia-Ocaña, Adolfo, Scott, Donald K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491153/ https://www.ncbi.nlm.nih.gov/pubmed/37693560 http://dx.doi.org/10.1101/2023.08.28.555207 |
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